Protein Alignment HDAC1 and hda-4

DIOPT Version :9

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001257278.1
• Gene: hda-4 / 181723
• WormBaseID: WBGene00001837
• Length: 869
• Species: Caenorhabditis elegans
• Alignment Length: 304
• Identity: 81/304 - (26%)
• Similarity: 147/304 - (48%)
• Gaps: 34/304 - (11%)

  Fly    32 RIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEYVRFLRSIRPD---NMSEYNKQMQRF- 92
            ||:...:.|:.:|..:|.|.....||:.:::...||..|..|. ::.|.   .:...:..::||
 Worm   489 RIQSIWSKLIEHGHVQKCEKVTAKKASLEQLQLVHSQTYTTFF-AVSPTACLKIDANSLPLKRFL 552

  Fly    93 -----NVGEDCPVF--DGLYEFCQLSAGGSVAAAVKLNKQASE-------ICINWGGGLHHAKKS 143
                 .:|.|...:  |...:.....|.|::   ::|:.|.:|       .||...|  |||:..
 Worm   553 QLPCGGIGVDSDTYFNDASTQTAARLAAGTL---IELSSQVAEGRLKNGFACIRPPG--HHAEHE 612

  Fly   144 EASGFCYVNDIVLGILEL-LKYH---QRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKY--GEY 202
            :|.|||:.|::.:.:..| .||.   .::..||.|||||:|.:.:|.....|:.:|.|::  |.:
 Worm   613 QAMGFCFFNNVAVAVKVLQTKYPAQCAKIAIIDWDVHHGNGTQLSFENDPNVLYMSLHRHDKGNF 677

  Fly   203 FPGTGDLRDIGAGKGKYYAVNIPLR-DGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLTG 266
            |||||.:.::|....|...||:|.. |.|.|..|.:.:..:|..||.:|.|..:::..|.|:..|
 Worm   678 FPGTGSVTEVGKNDAKGLTVNVPFSGDVMRDPEYLAAWRTVIEPVMASFCPDFIIVSAGFDACHG 742

  Fly   267 --DRLGCFNLTVKGHGKCVEFVKKY-NLPFLMVGGGGYTIRNVS 307
              :.||.:.:|.:..|...:.:..| :...::...|||.::::|
 Worm   743 HPNALGGYEVTPEMFGYMTKSLLNYASGKVVLALEGGYDLKSIS 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:388375	81/304 (27%)
hda-4	NP_001257278.1	HDAC_classIIa	460..834	CDD:212544	81/304 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910