Protein Alignment HDAC1 and hda-10

DIOPT Version :9

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_496910.1
• Gene: hda-10 / 175039
• WormBaseID: WBGene00001838
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 279
• Identity: 68/279 - (24%)
• Similarity: 120/279 - (43%)
• Gaps: 19/279 - (6%)

  Fly    56 KATADEMTKFHSDEYVRFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSV--AA 118
            :|...|:...|:..||..::|.....:.:......::   ||..|....:...:|:||.|:  ..
 Worm    58 EAEESEILAVHTKRYVDDVKSTETMTVEQQESFCTKY---EDIYVNSATWHRAKLAAGASIDLMT 119

  Fly   119 AVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEE 183
            :|...|:.....|...|  |||...|..|||..|::.:.....::..|:||.:|.|||.|:|.:|
 Worm   120 SVMAAKRPGIAFIRPPG--HHAMPDEGCGFCIFNNVAIAAKAAIQNGQKVLIVDYDVHAGNGTQE 182

  Fly   184 AF--YTTDRVMTVSFHKY--GEYFPGTGDLRDIGAGKGKYYAVNIPLRD-GMDDDAYESIFVPII 243
            ..  .....|..:|.|:|  |.::|   ::...|........:|:||.. |:.|..|.::|..||
 Worm   183 CVEQMGEGNVQLISIHRYENGHFWP---NMPQTGIYHNYKNTINLPLNTIGLTDADYHALFTHII 244

  Fly   244 SKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGGGGYTIRNVSR 308
            ...:..|||..:::..|.|:..||..|...:|..|....:..:....:|...:..|||.:..::.
 Worm   245 LPTIHAFQPDLLLVSSGFDASIGDPEGSMQVTPAGFATMIRMLIDTGIPVAALLEGGYFLDALAA 309

  Fly   309 CWTYETSVALAVEIANELP 327
                ::...|...:..|:|
 Worm   310 ----DSEWVLRALLGEEIP 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:388375	68/279 (24%)
hda-10	NP_496910.1	HDAC10_HDAC6-dom1	20..346	CDD:212526	68/279 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810