Protein Alignment HDAC1 and Hdac3

DIOPT Version :9

• Sequence 1: NP_647918.2
• Gene: HDAC1 / 38565
• FlyBaseID: FBgn0015805
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_034541.2
• Gene: Hdac3 / 15183
• MGIID: 1343091
• Length: 428
• Species: Mus musculus
• Alignment Length: 422
• Identity: 242/422 - (57%)
• Similarity: 328/422 - (77%)
• Gaps: 5/422 - (1%)

  Fly     7 KRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEYV 71
            |.|.|:||.|:||::||.||||||||:.:||:|:|:||||:||.:::|::|:..:|.:|||::|:
Mouse     3 KTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYI 67

  Fly    72 RFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGG 136
            .||:.:.|.||..:.|.:..||||:|||||.||:|||....|.|:..|.:||.:..:|.|||.||
Mouse    68 DFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGG 132

  Fly   137 LHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGE 201
            ||||||.||||||||||||:|||||||||.||||||||:||||||:||||.|||||||||||||.
Mouse   133 LHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGN 197

  Fly   202 Y-FPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLT 265
            | ||||||:.::||..|:||.:|:|||||:||.:|:.:|.|:||:|::.:||..:|||||||||.
Mouse   198 YFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVISQVVDFYQPTCIVLQCGADSLG 262

  Fly   266 GDRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGGGGYTIRNVSRCWTYETSVALAVEIANELPYND 330
            .||||||||:::|||:|||:||.:|:|.|::||||||:|||:||||||||:.:...|:.||||::
Mouse   263 CDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSE 327

  Fly   331 YFEYFGPDFKLHISPS-NMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPEDAINDESDDE 394
            |||||.|||.||...| .:.|||:.:||::|:..:||||:||.|||.|||..:|.|.:.  .|..
Mouse   328 YFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLT--YDRT 390

  Fly   395 DKVDKDDRLPQSDKDKRIVPENEYSDSEDEGE 426
            |:.|.::|.|:.:..:...| ||:.|.:.:.:
Mouse   391 DEADAEERGPEENYSRPEAP-NEFYDGDHDND 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC1	NP_647918.2	Arginase_HDAC	5..372	CDD:388375	224/366 (61%)
Hdac3	NP_034541.2	HDAC3	3..383	CDD:212529	232/379 (61%)
		Histone deacetylase	3..316		197/312 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	387..424		9/36 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D267420at33208
OrthoFinder	1	1.000	-	-		FOG0000617
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100248
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720