DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42540 and stoml1

DIOPT Version :9

Sequence 1:	NP_001246627.1	Gene:	CG42540 / 38562	FlyBaseID:	FBgn0260657	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	NP_001103502.1	Gene:	stoml1 / 563294	ZFINID:	ZDB-GENE-070209-241	Length:	410	Species:	Danio rerio

Alignment Length:	364	Identity:	100/364 - (27%)
Similarity:	166/364 - (45%)	Gaps:	68/364 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 HSHHALMQQSQQQQAIHRAEARRDTQAKHSHGFLY----SDEEISDKAS-----TCGKLLIFLSV 195
            :|||.           ||           .|.|.|    ...:.:||:.     .|..::.||..
Zfish    37 NSHHD-----------HR-----------GHSFDYVPKVHQNDYTDKSQGLLSWLCNLIVTFLVF 79

  Fly   196 ALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVP 260
            ....:|.|.|.:...|||..|||.|:|||||:..  .||||:..|||.||.:.|||||||.:::|
Zfish    80 LFTFVTFPISGWFVLKVVPNYERVVVFRLGRIRP--PKGPGVVLILPFIDQWQRVDLRTRAFNIP 142

  Fly   261 PQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMT 325
            |.:|.||||..|||.|.:.:|:.:..:|:..|::.:.||||.||..:..::..:.|.||.::|:.
Zfish   143 PCKVCTKDSGLVSVGADIQFRIWSPVMSVVAVQDLNSSTRLTAQNAMMTSLSKKSLREIQTDRLK 207

  Fly   326 ISGTMQVQLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAREA----RAKVIAAEG---- 382
            :...:.:.::|.|..||::|:|||:        :...:..|.:.....    ...|...||
Zfish   208 LGEHLGMDMNEMTKPWGLEVDRVEL--------ILEGVVREPDGGHSGPLIMPPSVPGLEGLTGP 264

  Fly   383 -EQKASRALRE--ASEVIGDSPA-ALQLRYLQTLNTISAEKNSTIVFPLPIDLI-------TYFL 436
             :|.|...|.:  ||:...|:.: :.:|..:.:::::: |...|:...|..:|:       .:.:
Zfish   265 IQQLAMHFLSQTTASQCTQDTVSFSDELHAVSSVSSVN-ELIETVRSVLSEELVHQVGACFHFHI 328

  Fly   437 KTNEATTQ-------QNARAAAAAIGNTPPPLQLAPQQQ 468
            .||...|.       |...|..|.:....|.:.|...:|
Zfish   329 TTNSGQTSSYYVDLTQGRGACGAGVLQREPDVSLCMSEQ 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42540	NP_001246627.1	HflC	188..440	CDD:223407	81/270 (30%)
CG42540	NP_001246627.1	SPFH_stomatin	229..430	CDD:259801	62/212 (29%)
stoml1	NP_001103502.1	PHB	94..232	CDD:214581	59/139 (42%)
		SPFH_SLP-1	109..239	CDD:259814	50/139 (36%)
		SCP2	301..405	CDD:280250	13/68 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062075at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820