Protein Alignment CG42540 and nphs2

DIOPT Version :10

• Sequence 1: NP_001246627.1
• Gene: CG42540 / 38562
• FlyBaseID: FBgn0260657
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001018155.2
• Gene: nphs2 / 557914
• ZFINID: ZDB-GENE-051102-2
• Length: 391
• Species: Danio rerio
• Alignment Length: 402
• Identity: 122/402 - (30%)
• Similarity: 207/402 - (51%)
• Gaps: 44/402 - (10%)

  Fly    53 DRDRERDHHLHHHQSNNVASSPLP--------VTASIQLHQQQPQQQQQQQPLTQLQQPQLRERE 109
            ::..|.:...|..:|..:...|.|        ...|::|  |:|.:::::...|:      .|.|
Zfish     7 EKRTETETSRHSSRSARIKREPSPSAKERKTKAAKSVKL--QEPHKRKEKLVTTE------EEEE 63

  Fly   110 HHQQQQQQQQQMMQQPQQQQQMQQPQQQLPHSHHALMQQSQQQQAIHRAEARRDTQAKHSHGFLY 174
            ....|......::.....::::::.:::|    .||::.....:.:.:         |:
Zfish    64 AKDAQIISSSTVVNVDSVRERIKEEREEL----LALLETEGPGEGLKK---------KY------ 109

  Fly   175 SDEEISDKASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFF 239
                    ...|..|||.|.:::||:.||.|::.|.|:|:|:||||.||||.|::...:|||:.|
Zfish   110 --------LGVCELLLIVLVLSVVILFLPISVWFCVKIVREHERAVKFRLGHLLKKRPRGPGLMF 166

  Fly   240 ILPCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQ 304
            .||.:|....||:|.:...:||..|:|||.|...|.||.|||:.|.:|..::..:.....:.|.|
Zfish   167 YLPFLDVCHIVDIRLQILKIPPHMVVTKDLVCTEVTAVCYYRIENVSVCYSSFASIPDVMQALTQ 231

  Fly   305 TTLRNTMGTRHLHEILSERMTISGTMQVQLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEA 369
            .::|..:.....::||.:|..|:..:||.||..|..||||||:.||:::.||.:||...|.||||
Zfish   232 VSVREILAHHAFNDILLDRKRIAQEIQVTLDSGTCRWGIKVEKAEIEEINLPPELQHNFAVEAEA 296

  Fly   370 AREARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDLITY 434
            .|:|:.||||||||:.|..||:.:.|.:..||..:.||.||.|:::.:|: ..:|..:|.|::|.
Zfish   297 RRQAQVKVIAAEGEKAACEALKASVESVSGSPLVMHLRLLQLLHSLRSEQ-PAVVLNIPPDVLTQ 360

  Fly   435 FLKTNEATTQQN 446
            .:.....|...|
Zfish   361 SIDLASLTRPAN 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42540	NP_001246627.1	SPFH_stomatin	229..430	CDD:259801	78/200 (39%)
nphs2	NP_001018155.2	SPFH_like	134..356	CDD:473137	91/222 (41%)