Protein Alignment CG42540 and STOML2

DIOPT Version :10

• Sequence 1: NP_001246627.1
• Gene: CG42540 / 38562
• FlyBaseID: FBgn0260657
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_038470.1
• Gene: STOML2 / 30968
• HGNCID: 14559
• Length: 356
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 82/317 - (25%)
• Similarity: 146/317 - (46%)
• Gaps: 68/317 - (21%)

  Fly   158 AEARRDTQAKHSHGFLYSDEEISDKASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIF 222
            |.|.|.|.|....|.|.:......:||:               .||.:..|.|  |.:.|..|:.
Human     3 ARAARGTGALLLRGSLLASGRAPRRASS---------------GLPRNTVVLF--VPQQEAWVVE 50

  Fly   223 RLGRLMQGGAKGPGIFFILPCIDSYARV-DLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNAT 286
            |:||..:  ...||:..::|.:|....| .|:....:||.|..:|.|:||:.:|.|:|.|:.:..
Human    51 RMGRFHR--ILEPGLNILIPVLDRIRYVQSLKEIVINVPEQSAVTLDNVTLQIDGVLYLRIMDPY 113

  Fly   287 VSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGTMQVQLDEATDAWGIKVERVEIK 351
            .:...||:..::...|||||:|:.:|...|.::..||.:::.::...:::|.|.|||:..|.|||
Human   114 KASYGVEDPEYAVTQLAQTTMRSELGKLSLDKVFRERESLNASIVDAINQAADCWGIRCLRYEIK 178

  Fly   352 DVRLPVQLQRAMAAEAEAAREARAKVIAAEGEQKA------------------------SRALRE 392
            |:.:|.:::.:|..:.||.|..||.|:.:||.:::                        ::|..|
Human   179 DIHVPPRVKESMQMQVEAERRKRATVLESEGTRESAINVAEGKKQAQILASEAEKAEQINQAAGE 243

  Fly   393 ASEVI---------------------GDSPAALQL--RYLQTLNTISAEKNSTIVFP 426
            ||.|:                     ||:.|:|.:  :|:...:.::.:.| ||:.|
Human   244 ASAVLAKAKAKAEAIRILAAALTQHNGDAAASLTVAEQYVSAFSKLAKDSN-TILLP 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42540	NP_001246627.1	SPFH_stomatin	229..430	CDD:259801	63/246 (26%)
STOML2	NP_038470.1	HflC	41..300	CDD:440099	69/262 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	321..356