Protein Alignment CG42540 and unc-24

DIOPT Version :10

• Sequence 1: NP_001246627.1
• Gene: CG42540 / 38562
• FlyBaseID: FBgn0260657
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_001355386.1
• Gene: unc-24 / 177594
• WormBaseID: WBGene00006761
• Length: 443
• Species: Caenorhabditis elegans
• Alignment Length: 317
• Identity: 81/317 - (25%)
• Similarity: 149/317 - (47%)
• Gaps: 60/317 - (18%)

  Fly   160 ARRDTQAKHSHG-FLYSDE-----EISDKASTCGKLLIF-LSVALVIMTLPFSLFVCFKVVQEYE 217
            ||:.....:.:| |.|:.:     |...|..:..:|||| :|...|:||:|.||....|.:...|
 Worm    74 ARQGMMLGNKYGNFTYTRDYGVNMEDDIKPLSAIELLIFCVSFLFVVMTMPLSLLFALKFISTSE 138

  Fly   218 RAVIFRLGRLMQGGAKGPGIFFILPCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRV 282
            :.|:.||||..:  .:||||..::||||:..:|.:....::|||.:::|.|...|.:.|.|:.::
 Worm   139 KLVVLRLGRAQK--TRGPGITLVIPCIDTTHKVTMSITAFNVPPLQIITTDRGLVELGATVFLKI 201

  Fly   283 SNATVSIANVENAHHSTRLLAQTTLRNTMGTRHLHEILSERMTISGTMQVQLDEATDAWGIKVER 347
            .:...::..|::.:.|.|     ||.|||    |:..:|::.....    :|...|..:|:::..
 Worm   202 RDPIAAVCGVQDRNASVR-----TLANTM----LYRYISKKRICDD----ELGSFTCQFGVEITD 253

  Fly   348 VEIKDVRLPVQLQR-AMAAEAEAAR---------------EARAKVIAAEGEQKASRALREASEV 396
            |||.||::..:.:. .|:|.:..|:               |..||..|||.:.|.:..|.:.|:|
 Worm   254 VEISDVKIVKEGENMGMSALSSVAKSDAGQQLWQVIGPVFEDFAKECAAEEKAKENAPLVDLSDV 318

  Fly   397 IGDSPA----------ALQLRYLQTLNTISAEK------------NSTIVFPLPIDL 431
            ...|.|          ::.:.:|.::.:::.::            |...:.|:.|||
 Worm   319 PSTSAAGTSTDTPNIPSIDIDHLISVASLAMDEHLVRLIGRVFQINCKDIEPICIDL 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42540	NP_001246627.1	SPFH_stomatin	229..430	CDD:259801	53/238 (22%)
unc-24	NP_001355386.1	SPFH_like	146..263	CDD:473137	37/131 (28%)
		SCP2	357..439	CDD:442486	5/19 (26%)