Protein Alignment CG42540 and Stom

DIOPT Version :9

• Sequence 1: NP_001246627.1
• Gene: CG42540 / 38562
• FlyBaseID: FBgn0260657
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_038543.1
• Gene: Stom / 13830
• MGIID: 95403
• Length: 284
• Species: Mus musculus
• Alignment Length: 263
• Identity: 179/263 - (68%)
• Similarity: 219/263 - (83%)
• Gaps: 0/263 - (0%)

  Fly   177 EEISDKASTCGKLLIFLSVALVIMTLPFSLFVCFKVVQEYERAVIFRLGRLMQGGAKGPGIFFIL 241
            |....:...||.:|:..|...||:|.|.|:::|.|:|:||||.:||||||::||||||||:||||
Mouse    21 ENSKTELGACGWILVAASFFFVIITFPISIWICIKIVKEYERVIIFRLGRILQGGAKGPGLFFIL 85

  Fly   242 PCIDSYARVDLRTRTYDVPPQEVLTKDSVTVSVDAVVYYRVSNATVSIANVENAHHSTRLLAQTT 306
            ||.||..:||:||.::|:||||||||||||:|||.||||||.|||:::||:.||..:||||||||
Mouse    86 PCTDSLIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTT 150

  Fly   307 LRNTMGTRHLHEILSERMTISGTMQVQLDEATDAWGIKVERVEIKDVRLPVQLQRAMAAEAEAAR 371
            |||.:||::|.:|||:|..|:..||..||:|||.|||||||||||||:|||||||||||||||||
Mouse   151 LRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERVEIKDVKLPVQLQRAMAAEAEAAR 215

  Fly   372 EARAKVIAAEGEQKASRALREASEVIGDSPAALQLRYLQTLNTISAEKNSTIVFPLPIDLITYFL 436
            ||||||||||||..|||||:|||.||.:|||||||||||||.||:||||||||||||:|::...:
Mouse   216 EARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLTTIAAEKNSTIVFPLPVDMLQGIM 280

  Fly   437 KTN 439
            .:|
Mouse   281 GSN 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42540	NP_001246627.1	HflC	188..440	CDD:223407	176/252 (70%)
		SPFH_stomatin	229..430	CDD:259801	154/200 (77%)
Stom	NP_038543.1	PHB	53..204	CDD:214581	105/150 (70%)
		SPFH_stomatin	73..274	CDD:259801	154/200 (77%)
		Required for homooligomerization. /evidence=ECO:0000250	265..273		7/7 (100%)
		Required for lipid raft association. /evidence=ECO:0000250	267..269		1/1 (100%)
		Interaction with LANCL1. /evidence=ECO:0000250	273..284		2/11 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850731
Domainoid	1	1.000	260	1.000	Domainoid score	I1957
eggNOG	1	0.900	-	-		E1_COG0330
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H81681
Inparanoid	1	1.050	362	1.000	Inparanoid score	I2174
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062075at2759
OrthoFinder	1	1.000	-	-		FOG0000760
OrthoInspector	1	1.000	-	-		otm43620
orthoMCL	1	0.900	-	-		OOG6_100539
Panther	1	1.100	-	-	LDO	PTHR10264
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2823
SonicParanoid	1	1.000	-	-		X2327
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790