Protein Alignment Tie and ptk6b

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_001070140.1
• Gene: ptk6b / 767734
• ZFINID: ZDB-GENE-060929-1150
• Length: 511
• Species: Danio rerio
• Alignment Length: 457
• Identity: 117/457 - (25%)
• Similarity: 183/457 - (40%)
• Gaps: 143/457 - (31%)

  Fly   746 YLVR-------NFVI----RRRAKQSEVFDVCITDQQPISPVKKVDSKYQVDDDEDEVDHQHHQH 799
            :|||       .:|:    :..||..::|..  .||..:..:.|..|..:|
Zfish   158 FLVRVSESDDMGYVLSVRTKENAKHFKIFQT--GDQFYVDALFKFSSIVEV-------------- 206

  Fly   800 MQHHQNHQNHQNHQHHQAMP------MSQASQRDANHNRYGNNDDKTSLASEFHDFERSNIRLKS 858
            ::|:|:|            |      :|:...|....|....:.|:..|..|       ..:|::
Zfish   207 IEHYQSH------------PLSIGDLLSEPCIRIKPENVPPPSTDEWELPKE-------EFQLEN 252

  Fly   859 LLGEGNFGQVWKAEADDLSGHFGATRIVAVKTIRACSAQVSLKD---EANIMRKLGSHQNVVTLL 920
            .||.|:|       ||..||.:.....||:|.::...|.| |::   |..||::| .|:::::|.
Zfish   253 QLGSGHF-------ADVYSGKWKNHSKVAIKILKNNDALV-LREFQLEVQIMKRL-RHKHLISLF 308

  Fly   921 GACVESEPHMLIMEYAMRGRLLSLLRAARSATNILPASVPGGRSLAPLSPRTLAGFALDIACGME 985
            ..|..|.|..:|.|...:|.||..||.            |.|||   |...:|...|..:|.||.
Zfish   309 AVCTSSSPFYIITELIEKGDLLHFLRN------------PEGRS---LQMESLIDMAAQVADGMA 358

  Fly   986 YIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKNAANDLMRHNAHKFKFDF 1050
            |:.....:||||||||||:....:|||.|||::      |:.||..
Zfish   359 YLEANNSIHRDLAARNVLVGDGYVCKIADFGLA------RIIKEPV------------------- 398

  Fly  1051 GSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPIRWMAPESLQYHMFTTET 1115
                                :.|.|     ||             :|.:|.|||::.:..:::::
Zfish   399 --------------------YLSDD-----KK-------------IPYKWTAPEAIGHGTYSSKS 425

  Fly  1116 DIWAFGIVLWEIATLGSTPYSQLTGREVIRRV-PQGLRPDLPKESRHEFYNLMSRCWHKEPHMRP 1179
            |:|:|||:|:||.|.|..||..:...||...: .:..|...|.:.....||:|..||..|...||
Zfish   426 DVWSFGILLYEIVTHGGIPYPGVNTGEVYDLITKENYRMPSPPKCPQAIYNIMRACWRIESVDRP 490

  Fly  1180 SF 1181
            :|
Zfish   491 NF 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	95/332 (29%)
		PTKc	860..1187	CDD:270623	94/326 (29%)
ptk6b	NP_001070140.1	SH3_Brk	70..126	CDD:212781
		SH2	132..216	CDD:214585	16/85 (19%)
		PTKc_Srm_Brk	241..502	CDD:133248	97/346 (28%)
		STYKc	250..499	CDD:214568	95/330 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539311at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010