DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tie and Pdgfrl

DIOPT Version :9

Sequence 1:NP_523928.1 Gene:Tie / 38559 FlyBaseID:FBgn0014073 Length:1233 Species:Drosophila melanogaster
Sequence 2:NP_081116.3 Gene:Pdgfrl / 68797 MGIID:1916047 Length:375 Species:Mus musculus


Alignment Length:195 Identity:40/195 - (20%)
Similarity:65/195 - (33%) Gaps:71/195 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 NNRKPDRKSAEKTI-------SQSSTARAATIILVLLFIFFSRYLVYASVTMSLMKIHRGNESFC 67
            |..||..|.|:..|       |..|||::.:|::..:                      ||..| 
Mouse    36 NRIKPTNKKAKPKIPKVKDRDSTDSTAKSQSIMMQAM----------------------GNGRF- 77

  Fly    68 SCWLLLLLLVALLLAEAIVAAAAATLSETQTNATNGAIREPPVQLQLQQQQLQLQLQLNATAGD- 131
               ......|:||..:.:......:..|....|.....::..:.::..::..||.| :|:||.| 
Mouse    78 ---QRPAATVSLLAGQTLELRCKGSKVEWSYPAYLDTFKDSRLTVKQSERYGQLTL-VNSTAADT 138

  Fly   132 GE-------------SRNSA-------------EIF--SPGDVDVVGDKPTTYRPSGANRPSIAP 168
            ||             .|:.|             |:|  ||...|||...|        :|.::.|
Mouse   139 GEFSCWEQLCNGYICRRDEAKTGSTYIFFTEKGELFVPSPSYFDVVYLNP--------DRQAVVP 195

  Fly   169  168
            Mouse   196  195

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TieNP_523928.1 TyrKc 854..1183 CDD:197581
PTKc 860..1187 CDD:270623
PdgfrlNP_081116.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 20..63 9/26 (35%)
Ig 80..143 CDD:299845 14/63 (22%)
IG_like 83..>143 CDD:214653 14/60 (23%)
I-set 272..373 CDD:254352
Ig 293..372 CDD:299845
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0200
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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