Protein Alignment Tie and ptk6a

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: XP_682778.6
• Gene: ptk6a / 555232
• ZFINID: ZDB-GENE-081105-117
• Length: 563
• Species: Danio rerio
• Alignment Length: 656
• Identity: 143/656 - (21%)
• Similarity: 232/656 - (35%)
• Gaps: 206/656 - (31%)

  Fly   564 TTTSSTTPSTTTTSSTSTTVIPTTTKANSIIEKDKELIRALGPALTR---EINIDDANNLIVFCN 625
            |:...|.....|.::..|..:|..::| |..|...||.:||.....|   |::..:.....: |.
Zfish    75 TSPDKTEAEKPTNTAKQTVNVPNPSRA-SACEPGSELYKALWSYKARGADELSFQEGEQFRI-CE 137

  Fly   626 NTS----------DCGVTPRTQTQPSHTTDSSPKILRTTVLTSIRSTVHPRPTSTSTTTSTTTTA 680
            ...          |..||.|... |:|             ..:.|.||..:|....|.....|..
Zfish   138 RQGEWWTALKLGRDGAVTGRGFV-PNH-------------FLARRQTVKEQPWYFGTLNRFETEI 188

  Fly   681 PPAVTAPSNEVYIGIVESSSSASPADISSTVIANERDLNMEMRRMNLVTLVLVAVGVIPLAAIIL 745
              .:.||.|:|...:|..|...:...:.| |::.:|...
Zfish   189 --LLLAPENDVGAFLVRHSEKDNIGYVLS-VLSGDRSRE-------------------------- 224

  Fly   746 YLVRNFVIRRRAKQSEVFDVCITDQQPISPVKKVDS--KYQVDDDEDEVDHQHHQHMQHHQNHQN 808
              |::..|.:...:|...|...|.|   |..|.||.  ||.:|.|.
Zfish   225 --VKHIKIHQNQNESFYLDKSQTFQ---SLEKLVDYYWKYSLDGDS------------------- 265

  Fly   809 HQNHQHHQAMPMSQASQRDANHNRYGNNDDKTSLASEFHDFE--RSNIRLKSLLGEGNFGQV--- 868
                ...|.....:...:|.:|             |..:|:|  :....|:..||:|.|..|
Zfish   266 ----FLKQPCRRPEPKPKDLSH-------------STVNDWELPKEEFTLEEELGKGFFADVYRG 313

  Fly   869 -WKAEADDLSGHFGATRIVAVKTIRACSAQVSLKD---EANIMRKLGSHQNVVTLLGACVESEPH 929
             ||...:           ||:|.::  :..::.::   |..|::|| .|::::.|...|..|.|.
Zfish   314 KWKGMVN-----------VAIKILK--NDSINHREFMLETQILKKL-RHKHLIALFAVCTSSSPF 364

  Fly   930 MLIMEYAMRGRLLSLLRAARSATNILPASVPGGRSLAPLSPRTLAGFALDIACGMEYIAGRRIVH 994
            .:|.|...:|.|||||:               |:....|:.:.|...|..:|.||.|:..:..:|
Zfish   365 YIITELMEKGDLLSLLK---------------GKEGQDLNAQMLTEMASQVADGMAYLEEQNSIH 414

  Fly   995 RDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKNAANDLMRHNAHKFKFDFGSRYILQHW 1059
            |||||||||:..|.:||:.|.|::      |:.||..
Zfish   415 RDLAARNVLVGANYICKVADLGLA------RIVKESV---------------------------- 445

  Fly  1060 QHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPIRWMAPESLQYHMFTTETDIWAFGIVL 1124
                       :.|:|.                  .:|.:|.|||::.:..|:.::|:|:||::|
Zfish   446 -----------YSSEDA------------------QIPYKWSAPEAISHGRFSNKSDVWSFGVLL 481

  Fly  1125 WEIATLGSTPYSQLTGREVIRRVPQGLRPDLPKESRHEFYNLMSRCWHKEPHMRPSFAQSRLEIT 1189
            :|:.|.|..||...:..||...:..|.|...|.......|::|..||......||.|:    |:.
Zfish   482 YEMFTYGGVPYPAFSNIEVYNMITSGYRMPAPPNCPSHIYDIMLMCWRYSAEERPDFS----ELL 542

  Fly  1190 RSLHKW 1195
            |.|..:
Zfish   543 RLLEDY 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	84/335 (25%)
		PTKc	860..1187	CDD:270623	83/333 (25%)
ptk6a	XP_682778.6	SH3_Brk	110..167	CDD:212781	12/71 (17%)
		SH2	174..261	CDD:214585	24/120 (20%)
		PKc_like	289..541	CDD:328722	85/347 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539311at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010