DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tie and fgfrl1a

DIOPT Version :9

Sequence 1:	NP_523928.1	Gene:	Tie / 38559	FlyBaseID:	FBgn0014073	Length:	1233	Species:	Drosophila melanogaster
Sequence 2:	NP_956670.1	Gene:	fgfrl1a / 393347	ZFINID:	ZDB-GENE-040128-2	Length:	483	Species:	Danio rerio

Alignment Length:	104	Identity:	26/104 - (25%)
Similarity:	39/104 - (37%)	Gaps:	27/104 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   602 RALGPAL-TREINIDDANNLIVFCNNTSDC--------------------GVTPRTQTQPSHTTD 645
            |.|..|| .:|:..|||...|  |..|:..                    |..|..:|:  ::||
Zfish    73 RVLQQALRIKEVEADDAGTFI--CKATNGFGSVNINYTLIVIDDSSAGREGARPAGETE--YSTD 133

  Fly   646 SSPKILRT--TVLTSIRSTVHPRPTSTSTTTSTTTTAPP 682
            .:.|::|.  |....:|..|..||..:|.....|.:..|
Zfish   134 LTGKLVRPRFTQPAKMRKRVIARPVGSSVRLKCTASGNP 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581
Tie	NP_523928.1	PTKc	860..1187	CDD:270623
fgfrl1a	NP_956670.1	I-set	32..111	CDD:254352	11/39 (28%)
		IGc2	38..101	CDD:197706	11/29 (38%)
		I-set	141..232	CDD:254352	8/32 (25%)
		Ig2_FGFRL1-like	151..232	CDD:143264	6/22 (27%)
		I-set	245..349	CDD:254352
		Ig	255..350	CDD:299845
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900