Sequence 1: | NP_523928.1 | Gene: | Tie / 38559 | FlyBaseID: | FBgn0014073 | Length: | 1233 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_002244.1 | Gene: | KDR / 3791 | HGNCID: | 6307 | Length: | 1356 | Species: | Homo sapiens |
Alignment Length: | 1105 | Identity: | 243/1105 - (21%) |
---|---|---|---|
Similarity: | 388/1105 - (35%) | Gaps: | 399/1105 - (36%) |
- Green bases have known domain annotations that are detailed below.
Fly 286 LFSDESSHGLFVVAKEQNGTLNHIADGTKPAV-MGKGIPSKTNSMEDDVEEEEDELK--PYVYFG 347
Fly 348 AKLPPIR--PGGL------TIKAAEGDDDHP-RVLEVSVAQSTTPTITTTSTTPAPVSSTR---- 399
Fly 400 --------PTASTRRPLTPVERSRSKYKYHMRERGLVPT------AAPPP-------------AA 437
Fly 438 PPAPPVSRTR------------YVGSGRPTAGLSDSIQDLKQTESEVA------KPVVRRVVQKV 484
Fly 485 SPSSSTPLIITVLSAEEETTVGQTEALPTDESTTTTSTTTTTEKPSTTTSTSTTTTTPVPSTSKR 549
Fly 550 TT------TNAPLSTTNTPTTTTSSTTPSTTTTSSTSTTVIPTTTKANSIIEKDKELIRALGPAL 608
Fly 609 TREINIDDANNLIVFCNNTSDCGVTPRTQTQPSHTTDSSPKILRTTVLTSIRSTV----HPRPTS 669
Fly 670 TSTTTSTTTTA----PPAVT-APSNEVYIGIVESSSSASPADISSTVIANERDLNMEMRRM---- 725
Fly 726 ------------------------------NLVTLVLVAVGVIPLAAIILYLVRNFVIR--RRAK 758
Fly 759 QSEVFDVCITDQQPISPVKKVDSKYQVDDDEDEVDHQHHQHMQHHQNHQNHQNHQHHQAMPMSQA 823
Fly 824 SQRDANHNRYGNNDDKTSLASEFHDFERSNIRLKSLLGEGNFGQVWKAEADDLSGHFG----AT- 883
Fly 884 RIVAVKTIR---ACSAQVSLKDEANIMRKLGSHQNVVTLLGACVE-SEPHMLIMEYAMRGRLLSL 944
Fly 945 LRAARSATNILPASVPGGR-------------------------------------SL------- 965
Fly 966 AP-------LSPRTLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDL-- 1021
Fly 1022 DAERMRKEQEKNAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHG 1086
Fly 1087 HDTIGKRHALPIRWMAPESLQYHMFTTETDIWAFGIVLWEIATLGSTPYSQL-TGREVIRRVPQG 1150
Fly 1151 LRPDLPKESRHEFYNLMSRCWHKEPHMRPSFAQSRLEITRSLHKWVDDDSAASDYMDVSGFSEDL 1215
Fly 1216 1215 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Tie | NP_523928.1 | TyrKc | 854..1183 | CDD:197581 | 115/391 (29%) |
PTKc | 860..1187 | CDD:270623 | 114/389 (29%) | ||
KDR | NP_002244.1 | Ig | 41..109 | CDD:299845 | |
IG_like | 231..324 | CDD:214653 | 6/22 (27%) | ||
Ig1_VEGFR | 239..326 | CDD:143270 | 6/24 (25%) | ||
IG_like | 340..417 | CDD:214653 | 21/85 (25%) | ||
Ig2_VEGFR-2 | 348..417 | CDD:143272 | 18/77 (23%) | ||
Ig_2 | 551..661 | CDD:290606 | 17/140 (12%) | ||
IG | 565..661 | CDD:214652 | 15/126 (12%) | ||
I-set | 667..754 | CDD:254352 | 15/99 (15%) | ||
IGc2 | 680..744 | CDD:197706 | 12/76 (16%) | ||
PTKc_VEGFR2 | 826..1167 | CDD:270681 | 118/412 (29%) | ||
Pkinase_Tyr | 834..1160 | CDD:285015 | 115/396 (29%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1274..1318 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |