Protein Alignment Tie and Ptk6

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_001102438.1
• Gene: Ptk6 / 366275
• RGDID: 1309098
• Length: 451
• Species: Rattus norvegicus
• Alignment Length: 475
• Identity: 120/475 - (25%)
• Similarity: 182/475 - (38%)
• Gaps: 140/475 - (29%)

  Fly   746 YLVRNFVIRRRAKQSEV-FDVCITDQQPISPVK-----------KVDSKYQVDD-----DEDEVD 793
            |:..|::..:...:||. |..||:..:.:..::           :|..|...|.     |.:.|.
  Rat    61 YVPHNYLAEKETVESEPWFFGCISRSEAMHRLQSEDYPKGTFLIRVSQKPGADYVLSVWDAEAVR 125

  Fly   794 HQHHQHMQHHQNHQN--------------HQNHQHHQAMPMSQASQRDANHNRYGNNDDKTSLAS 844
            |.........:.|.|              |:.|.....:.:|.|..:           .||....
  Rat   126 HYRIWRNSAGRLHLNEVVSFSSLSELVNYHKTHNLSPGLQLSMACWK-----------LKTEPLP 179

  Fly   845 EFHDFE--RSNIRLKSLLGEGNFGQV----WKAEADDLSGHFGATRIVAVKTIRACSA--QVSLK 901
            .:.|:|  |....|...||.|.||:|    ||          |..| ||||.|...:.  |.:.:
  Rat   180 HWDDWERPREEFTLCKKLGSGYFGEVFEGLWK----------GLVR-VAVKVISRDNLLHQHTFQ 233

  Fly   902 DEANIMRKLGSHQNVVTLLGACVESEPHMLIMEYAMRGRLLSLLRAARSATNILPASVPGGRSLA 966
            .|...|:|| .|:::::|.......:|..:|.|...:|.||.|||  .|....||.
  Rat   234 AEIQAMKKL-RHKHILSLYAVATAGDPVYIITELMPKGSLLQLLR--DSDEKDLPI--------- 286

  Fly   967 PLSPRTLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQE 1031
                ..|..||..:|.||.|:..:..:||||||||||:..|.:||:.|||::      |:.||
  Rat   287 ----LELVDFASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVGDFGLA------RLVKE-- 339

  Fly  1032 KNAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHAL 1096
                 |:                                :.|:|                  |.:
  Rat   340 -----DI--------------------------------YLSRD------------------HNV 349

  Fly  1097 PIRWMAPESLQYHMFTTETDIWAFGIVLWEIATLGSTPYSQLTGREVIRRVPQGLRPDLPKESRH 1161
            |.:|.|||:|....::.::|:|:||::|.||.:.|..||..::..|...||..|.|...|.|...
  Rat   350 PYKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRVDAGYRMPCPLECPP 414

  Fly  1162 EFYNLMSRCWHKEPHMRPSF 1181
            ..:.||..||.::|..||.|
  Rat   415 NIHKLMLSCWSRDPKQRPCF 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	96/334 (29%)
		PTKc	860..1187	CDD:270623	95/328 (29%)
Ptk6	NP_001102438.1	SH3_Brk	12..69	CDD:212781	2/7 (29%)
		SH2_PTK6_Brk	75..174	CDD:198221	17/109 (16%)
		PKc_like	184..444	CDD:304357	98/341 (29%)
		STYKc	192..441	CDD:214568	96/333 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539311at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010