Protein Alignment Tie and Y50D4B.6

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_503375.2
• Gene: Y50D4B.6 / 3565593
• WormBaseID: WBGene00021745
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 486
• Identity: 109/486 - (22%)
• Similarity: 195/486 - (40%)
• Gaps: 132/486 - (27%)

  Fly   728 VTLVLVAVGVIPLAAIILYLVRNFVIRR------RAKQSEVFDVCITDQQPISPVKKVDSKYQVD 786
            :.::...:.||.|:.:..|:.:.:.:|:      |:.:|.:  :..:.|:..|.|::.:|..|.:
 Worm     6 ILVIFYCIVVIALSVLFYYVWKFYYLRKEEHEETRSLESGI--IHSSSQKTPSSVRENESLLQAN 68

  Fly   787 DDEDEVDHQHHQHMQHHQNHQNHQNHQHHQAMPMSQASQRDANHNRYGNNDDKTSLASEFHDFER 851
            ::...:.                     .:..|::...:......|:..:.:|.|    |::.
 Worm    69 EENVPIG---------------------LETEPINAIIKNLKFDERFEIDVNKFS----FYNL-- 106

  Fly   852 SNIRLKSLLGEGNFGQVW-----KAEADDLSGHFGATRIVAVKTIRAC-----SAQVSLKDEANI 906
                  |.||.|.:|:|:     |.:.:.|.......  ||||  ||.     |.|..:.:|.|:
 Worm   107 ------SFLGNGYYGKVFKERMHKKQKNGLDSENSLE--VAVK--RALRPEDPSEQQLMCEELNV 161

  Fly   907 MRKLGSHQNVVTLLGACVESEPHMLIMEYAMRGRLLSLLRAARSATN-ILPASVPGGRSLAPLSP 970
            |..:|.|.|::.|: ..:.:...:::.|:..:|.|:..|||.|...| .:......||.|.|..
 Worm   162 MCVVGKHPNILALI-RWIRTNEILIVSEFVEKGDLVEYLRARRRYFNKDIVCVEDNGRLLCPTD- 224

  Fly   971 RTLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKNAA 1035
              |..||..||.||:::.....||||||.|||.:..|.:.:|.|||
 Worm   225 --LLSFAFQIANGMKFLGNVACVHRDLALRNVFVKRNRIIRIADFG------------------- 268

  Fly  1036 NDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPIRW 1100
                                |..|                  |..|:.:.....:|    .|::|
 Worm   269 --------------------LARW------------------HENKEYYRKKTDVG----FPMKW 291

  Fly  1101 MAPESLQYHM------FTTETDIWAFGIVLWEIATLGSTPYSQLTGRE-----VIRRVPQGLRPD 1154
            :|||..::..      |.:::|||::|:.|:||.:||.:||..|..|.     :::.|..|.:..
 Worm   292 LAPECFEFEQERENIKFDSKSDIWSYGVCLYEIFSLGVSPYEGLDFRPDYFQGLMKYVRDGNQLP 356

  Fly  1155 LPKESRHEFYNLMSRCWHKEPHMRPSFAQSR 1185
            .|:....:.|..|..||:..|..||.|::.|
 Worm   357 SPEHGSDKIYEFMQSCWNLNPDKRPVFSECR 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	91/350 (26%)
		PTKc	860..1187	CDD:270623	91/348 (26%)
Y50D4B.6	NP_503375.2	PTKc	109..391	CDD:270623	91/348 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910