Protein Alignment Tie and Ror

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_476962.1
• Gene: Ror / 34367
• FlyBaseID: FBgn0010407
• Length: 685
• Species: Drosophila melanogaster
• Alignment Length: 391
• Identity: 111/391 - (28%)
• Similarity: 166/391 - (42%)
• Gaps: 93/391 - (23%)

  Fly   826 RDANHNRYGNNDDKTSLASE---------FHDFERSNIRLKSLLGEGNFGQVWKAEADDLSGHFG 881
            :||.....||..|..:|.|:         .:.|...::.....||||.||:|:|.:   |.....
  Fly   373 QDAGRGNLGNLSDHVALNSKLIERNTLLRINHFTLQDVEFLEELGEGAFGKVYKGQ---LLQPNK 434

  Fly   882 ATRIVAVKTIR---ACSAQVSLKDEANIMRKLGSHQNVVTLLGACVESEPHMLIMEYAMRGRLLS 943
            .|..||:|.::   :...|...|.|..::..| .|||:|.:||..:..||:.::.||...|.|..
  Fly   435 TTITVAIKALKENASVKTQQDFKREIELISDL-KHQNIVCILGVVLNKEPYCMLFEYMANGDLHE 498

  Fly   944 LLRAARSATNILPASVPGGRSLAPLSPRTLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNG 1008
            .| .:.|.|.        |:||:.|.   ....||.|:.||:|::....|||||||||.|::...
  Fly   499 FL-ISNSPTE--------GKSLSQLE---FLQIALQISEGMQYLSAHHYVHRDLAARNCLVNEGL 551

  Fly  1009 MCKICDFGMSIDLDAERMRKEQEKNAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCS 1073
            :.||.|||:|.|:.:....:.|.|:
  Fly   552 VVKISDFGLSRDIYSSDYYRVQSKS---------------------------------------- 576

  Fly  1074 KDQPHGEKKSHHGHDTIGKRHALPIRWMAPESLQYHMFTTETDIWAFGIVLWEIATLGSTPYSQL 1138
                                 .||:|||..||:.|..||||:|:|:||:|||||.:.|..||...
  Fly   577 ---------------------LLPVRWMPSESILYGKFTTESDVWSFGVVLWEIYSYGMQPYYGF 620

  Fly  1139 TGREVIRRVPQGLRPDLPKESRHEFYNLMSRCWHKEPHMRPSFAQSRLEITRSLHKWVDDDSAAS 1203
            :.:|||..:........|:......|:||..|||::...||:|.    :|:..|..|.:....||
  Fly   621 SNQEVINLIRSRQLLSAPENCPTAVYSLMIECWHEQSVKRPTFT----DISNRLKTWHEGHFKAS 681

  Fly  1204 D 1204
            :
  Fly   682 N 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	98/331 (30%)
		PTKc	860..1187	CDD:270623	98/329 (30%)
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568
		KR	235..312	CDD:214527
		PTKc_Ror	404..673	CDD:270642	101/349 (29%)
		Pkinase_Tyr	410..670	CDD:285015	99/340 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455324
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940