Protein Alignment Tie and CG3277

DIOPT Version :10

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_608762.3
• Gene: CG3277 / 33543
• FlyBaseID: FBgn0031518
• Length: 789
• Species: Drosophila melanogaster
• Alignment Length: 914
• Identity: 197/914 - (21%)
• Similarity: 318/914 - (34%)
• Gaps: 329/914 - (35%)

  Fly   476 VVRRVVQKVSPSSST--PLIITVLSAEEET--------TVGQTEALPTDESTTTTSTTTTTEKPS 530
            :||..|.:....::|  .||..|.|:|:|.        ..|.:|.:..:..|..........:.:
  Fly    19 LVRNAVGQAPRENATNPTLISLVRSSEKEPEQMESHRYVTGLSEPIAMEPLTRMRLNPNPDGEIT 83

  Fly   531 TTTSTSTTTTTPVPSTSKRTTTNAPLSTTNT--PTTTTSSTTPST----------TTTSSTSTTV 583
            ..|:..|.....:|....|...|.|..|:..  .:...:|..|..          ..::.|.:..
  Fly    84 ELTTNVTLYMEKIPRLQVRWQDNLPQGTSYNVLVSAVNNSRCPDAPCSEYGIKEKNASAETHSVN 148

  Fly   584 IPTTTKAN---------------SIIEKDKELIR---------------------------ALGP 606
            :|.....|               .|:|....::|                           |:..
  Fly   149 LPVNPNLNVESVDCNYMFGCQYQVIVETSNAMVRRSARVYIPQCLEGKCSCQLAPTPPKVLAVAK 213

  Fly   607 ALTRE---INIDDANNLIVFCNNTSDCGVTPRT---------QTQPSHTTDSSPKILRTTV--LT 657
            .|:.|   ||:....:.::.....|....|.||         :|.||.......|.|.|.|  |:
  Fly   214 MLSNETISINLSILASELLRKEQDSHLHETLRTYKMQLKINEETNPSLPWGGVLKHLMTRVYKLS 278

  Fly   658 SIRSTVHPR----------------------------PTSTSTTTSTTTTAPPAVTAPSNEVYIG 694
            .:.....|:                            ||......|.|     .|..|:|.|.
  Fly   279 ELNFRATPKGFEGVMKLGLGTQLKEKASLSLQAVIIDPTGCEGPRSVT-----KVPVPANPVL-- 336

  Fly   695 IVESSSSASPADISSTVIANERDLNMEMRRMNLVTLVLVAVGVIPLAAIILYLVRNFVIRRRAKQ 759
            :.|..|      :|:::|              :::.:|:|   |.||.:|:.|:|    ||||:.
  Fly   337 LTEGDS------VSNSII--------------VMSAMLIA---IILAGLIMLLLR----RRRART 374

  Fly   760 SEVFDVCITDQQPISPVKKVDSKYQVDDDEDEVDHQHHQHMQHHQNHQNHQNHQHHQAMPMSQAS 824
            :    ..:..|:.|.......|..:::|:.:.||
  Fly   375 T----AKLRKQEQIYIQTFATSAIEMEDNVNYVD------------------------------- 404

  Fly   825 QRDANHNRYGNNDDKTSLASEFHDFERSNIRLKSLLGEGNFGQVWKAEADDLSGHFGATRIVAVK 889
                   :|........||..| :...|.|::..:||||.||||.:|.|.:|....|.| |||||
  Fly   405 -------KYVEKSQVLGLADIF-EVPHSAIQIGRMLGEGAFGQVHEATAINLRRMRGTT-IVAVK 460

  Fly   890 TIRACSAQVSLKD---EANIMRKLGSHQNVVTLLGACVESEPHMLIMEYAMRGRLLSLLRAARSA 951
            .::.......:.:   |..:::.:|:|.|||:.||.|....|:::||||..:|.|||.||..|..
  Fly   461 QLKPNPKADEVAEYLAEIEMLKGVGTHHNVVSFLGCCTIKPPYLMIMEYVNKGNLLSYLRTVRKE 525

  Fly   952 TNILPASVPGGRSLAPLSPRT-------------------------------------------- 972
            .:.|........|..|:..||
  Fly   526 ASKLRNRNANYTSCRPIMTRTNSTSSPKSQSVNYIELKASSQTIEMPQEDSTAHMNGIRQPHPSF 590

  Fly   973 ----------------------LAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDF 1015
                                  |..|||.||.||.::..:.|.||||||||||:|.|...||.||
  Fly   591 AETTYTIVEDEDAFEYILDNKELHNFALQIANGMRFLEEQEITHRDLAARNVLIDSNKTLKISDF 655

  Fly  1016 GMSIDLDAERMRKEQEKNAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGE 1080
            |:
  Fly   656 GL--------------------------------------------------------------- 657

  Fly  1081 KKSHHGHDTIGKRHALPIRWMAPESLQYHMFTTETDIWAFGIVLWEIATLGSTPYSQLTGREVIR 1145
              |.||..|..:...||:||::.|:::.:::::::||||:|:|||||.|||::||..::..|:|.
  Fly   658 --SRHGIYTNTRTRKLPLRWLSIEAIRENVYSSKSDIWAYGVVLWEIGTLGASPYPTISNDELIP 720

  Fly  1146 RVPQGLRPDLPKESRHEFYNLMSRCWHKEPHMRPSFAQSRLEITRSLHKWVDDDSAASDYMDVSG 1210
            .:..|.|.:.|:....:.|.:|.:||.:||..||:|        .:|:|.:   |..:.|:|::.
  Fly   721 FLMAGNRLERPEICTPQVYTIMLQCWLEEPEERPTF--------DALYKVL---SPKTTYVDINS 774

  Fly  1211 FSED 1214
            .|:|
  Fly   775 LSDD 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	109/397 (27%)
CG3277	NP_608762.3	PTKc	430..763	CDD:270623	110/406 (27%)