Protein Alignment Tie and Ptk6

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_033210.1
• Gene: Ptk6 / 20459
• MGIID: 99683
• Length: 451
• Species: Mus musculus
• Alignment Length: 465
• Identity: 117/465 - (25%)
• Similarity: 189/465 - (40%)
• Gaps: 120/465 - (25%)

  Fly   746 YLVRNFVIRRRAKQSEV-FDVCITDQQPISPVKKVDSK--------YQVDDDEDEVDHQHHQHMQ 801
            |:..|::..:...:||. |..||:..:.:..::..|:.        .|....:..:..:..|.::
Mouse    61 YVPHNYLAEKETVESEPWFFGCISRSEAMHRLQAEDNSKGAFLIRVSQKPGADYVLSVRDAQAVR 125

  Fly   802 HHQNHQNHQNHQH-HQAMPMSQASQRDANHNRYGNN----------DDKTSLASEFHDFE--RSN 853
            |::..:|::...| ::|:..|..|:....|.....:          ..||.....:.|:|  |..
Mouse   126 HYRIWKNNEGRLHLNEAVSFSNLSELVDYHKTQSLSHGLQLSMPCWKHKTEPLPHWDDWERPREE 190

  Fly   854 IRLKSLLGEGNFGQV----WKAEADDLSGHFGATRIVAVKTIRACSA--QVSLKDEANIMRKLGS 912
            ..|...||.|.||:|    ||.:..           ||||.|...:.  |.:.:.|...|:|| .
Mouse   191 FTLCKKLGAGYFGEVFEALWKGQVH-----------VAVKVISRDNLLHQHTFQAEIQAMKKL-R 243

  Fly   913 HQNVVTLLGACVESEPHMLIMEYAMRGRLLSLLR-AARSATNILPASVPGGRSLAPLSPRTLAGF 976
            |:::::|.......:|..:|.|...:|.||.||| :...|..||                .|..|
Mouse   244 HKHILSLYAVATAGDPVYIITELMPKGNLLQLLRDSDEKALPIL----------------ELVDF 292

  Fly   977 ALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKNAANDLMRH 1041
            |..:|.||.|:..:..:||||||||||:..|.:||:.|||::      |:.||       |:
Mouse   293 ASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVGDFGLA------RLVKE-------DI--- 341

  Fly  1042 NAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPIRWMAPESL 1106
                        |:                           ||        .|.:|.:|.|||:|
Mouse   342 ------------YL---------------------------SH--------EHNVPYKWTAPEAL 359

  Fly  1107 QYHMFTTETDIWAFGIVLWEIATLGSTPYSQLTGREVIRRVPQGLRPDLPKESRHEFYNLMSRCW 1171
            ....::.::|:|:||::|.||.:.|..||..::..|...||..|.|...|.|.....:.||..||
Mouse   360 SRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRVDAGYRMPCPLECPPNIHKLMLSCW 424

  Fly  1172 HKEPHMRPSF 1181
            .::|..||.|
Mouse   425 SRDPKQRPCF 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	95/335 (28%)
		PTKc	860..1187	CDD:270623	94/329 (29%)
Ptk6	NP_033210.1	SH3	12..69	CDD:302595	2/7 (29%)
		SH2_PTK6_Brk	75..174	CDD:198221	15/98 (15%)
		Linker	171..190		5/18 (28%)
		PKc_like	184..444	CDD:304357	97/342 (28%)
		STYKc	192..441	CDD:214568	95/334 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539311at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010