Protein Alignment Tie and old-1

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_496130.2
• Gene: old-1 / 191737
• WormBaseID: WBGene00003862
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 391
• Identity: 108/391 - (27%)
• Similarity: 161/391 - (41%)
• Gaps: 105/391 - (26%)

  Fly   860 LGEGNFGQVWKA--EADDLSGHFGATRI-VAVKTIRACSAQVS---LKDEANIMRKLGSHQNVVT 918
            ||.|.||.:.|.  .:.:.......:|: ||||.......|:.   :.||..:|..:|.|.|::.
 Worm   181 LGSGEFGIIRKGFLRSKNSKNEEKESRLEVAVKLPLNEYNQIQQELIYDELKVMCAVGKHPNILA 245

  Fly   919 LLGACVESEPHMLIMEYAMRGRLLSLLRAAR-SATN---ILPASVPGGRSLAPLSPRTLAGFALD 979
            |:|.....|..|::.|:...|.|||.||..| ..||   .|......      ||...|..||..
 Worm   246 LVGGITFGERKMIVSEFVENGDLLSFLRDNRIYFTNDQWTLETEQDS------LSLVDLLSFAFQ 304

  Fly   980 IACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKNAANDLMRHNAH 1044
            ||.||||:.....||||||.||||:..|.:.:|.|||::                       ..|
 Worm   305 IAKGMEYLIHVPCVHRDLALRNVLIKKNRIIRIADFGLA-----------------------RRH 346

  Fly  1045 KFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPIRWMAPESLQYH 1109
            |.| |:   |..|               |.|.|                  |||.||||||:...
 Worm   347 KNK-DY---YKTQ---------------SVDTP------------------LPIHWMAPESIDKL 374

  Fly  1110 MFTTETDIWAFGIVLWEIATLGSTPYSQLT--------GREVIRRVPQGLRPDLPKESRHEFYNL 1166
            :||.::|:|::|:.|:|:.:||.:||..:.        .:.|:..:.:|.|...|..:..|.||:
 Worm   375 LFTQKSDVWSYGVCLYELFSLGKSPYENVIKYDQRDFYWKYVLSYLNEGKRLAQPAHADAEIYNV 439

  Fly  1167 MSRCWHKEPHMRPSFA---------------QSRLEITRSLHKWVDDDSAASDYMDVSGFSEDLE 1216
            |..||..:.:.|.:|.               :..|::||.|.      |..::.:.:|.:..|.:
 Worm   440 MKLCWDLDMNSRTTFLDCIEFFEKELKTTSNEYFLDLTRKLR------SETNNQLRLSNWLSDEK 498

  Fly  1217 H 1217
            |
 Worm   499 H 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	100/355 (28%)
		PTKc	860..1187	CDD:270623	100/359 (28%)
old-1	NP_496130.2	TyrKc	175..461	CDD:197581	100/345 (29%)
		PTKc	179..462	CDD:270623	100/346 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910