Protein Alignment Tie and R09D1.13

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_496022.1
• Gene: R09D1.13 / 187740
• WormBaseID: WBGene00011169
• Length: 388
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 114/518 - (22%)
• Similarity: 185/518 - (35%)
• Gaps: 181/518 - (34%)

  Fly   725 MNLVTLVLVAVGVIPLA-AIILYLV-----RNFVIRRRAKQSEVFDVCITDQQPISPVKKVDSKY 783
            |:||.|:.:.:.||..| |.||..|     ::....||.|:..     ||:|..::|:.|.|...
 Worm     3 MDLVILICIFIAVILFAFACILQKVYKKKTQDRPALRRGKRGS-----ITEQIELTPINKDDMCI 62

  Fly   784 QVDDDEDEVDHQHHQHMQHHQNHQNHQNHQHHQAMPMSQASQRDANHNRYGNNDDKTSLASEFHD 848
            :                                                     |..|:.:...:
 Worm    63 R-----------------------------------------------------DNISIGNIPVE 74

  Fly   849 FERSNIRLKSLLGEGNFGQVWKAEADDLSGHFGATRI--------------VAVKTIRACSAQVS 899
            .:.||::..|:|..|.|.::.:          |...|              |.||..:....:..
 Worm    75 IDPSNLKFSSVLENGYFCKIRR----------GTLNINVTAEEKNSNKLVDVLVKRPKNHIEKEM 129

  Fly   900 LKDEANIMRKLGSHQNVVTLLGACVESEP----HMLIMEYAMRGRLLSLLRAARSATNILPASVP 960
            |::|..|:|.:|.|.||:.|:|   .:.|    .:::.|....|.|..:|:..::...::.....
 Worm   130 LENELTILRLIGRHPNVLALIG---YTSPMFGRTVVVYESVELGNLQHVLKITKNNFELVGVPET 191

  Fly   961 GGRSLAPLSPRTLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAER 1025
            ....|.......|..||..||.||||:....::||.||.||:.|..|...:|.:||:|
 Worm   192 EFSGLDEFCVSDLHSFAFQIANGMEYLTHIPVIHRFLALRNIFLKRNKTIRIANFGLS------- 249

  Fly  1026 MRKEQEKNAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTI 1090
                  || .||.              |.|                .|.|.|
 Worm   250 ------KN-VNDY--------------RII----------------DSMDTP------------- 264

  Fly  1091 GKRHALPIRWMAPESLQYHMFTTETDIWAFGIVLWEIATLGSTPYSQLTG--REVIRRVPQGLRP 1153
                 :|:.||||||....:|..:||:|:||:.|:|:.:||..||..:..  ..::..:.:|.|.
 Worm   265 -----VPLYWMAPESYNELIFNEKTDVWSFGVCLYELYSLGEDPYENVKTLFDHLMEYLEKGNRL 324

  Fly  1154 DLPKE-SRHEFYNLMSRCWHKEPHMRPSFA---------------------QSRLEITRSLHK 1194
            ..||. ...|.::.|..||:.:|..||.|:                     ||.|::..::.|
 Worm   325 SKPKYIDSPEIFDFMKICWNFKPETRPCFSDCAQFFKSHLQEFPPALLEQTQSELKLESNIRK 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	86/370 (23%)
		PTKc	860..1187	CDD:270623	87/368 (24%)
R09D1.13	NP_496022.1	STYKc	80..360	CDD:214568	86/354 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910