Protein Alignment Tie and W03A5.1

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_498153.3
• Gene: W03A5.1 / 175744
• WormBaseID: WBGene00020966
• Length: 803
• Species: Caenorhabditis elegans
• Alignment Length: 412
• Identity: 90/412 - (21%)
• Similarity: 143/412 - (34%)
• Gaps: 122/412 - (29%)

  Fly   801 QHHQNHQNHQNHQHHQAMPMSQASQRDANHNRYGNNDDKTSLASEFHDFERSNIRLKSL------ 859
            :||:..:|..|....:...:|...:......::.|        ...|:   ::||:.||
 Worm   438 KHHERLKNRLNLSKEEKELVSSYMKNQGPQKKWEN--------MPLHE---TSIRINSLFYVDGK 491

  Fly   860 --------LGEGNFGQVWKAEADDLSGHFGATRIVAVKTIRACSAQVSLKDEAN------IMRKL 910
                    :|:|.||.|.|.:   .....|.:..||||.:   ..:.|.|||.|      .:.::
 Worm   492 KIDCGTDQIGKGAFGTVKKGK---FRNSLGESVPVAVKKL---GLRESSKDERNPAFSEMEILEM 550

  Fly   911 GSHQNVVTLLGACVESEPHMLIMEYAMRGRLLSLLRAARSATNILPASVPGGRSLAPLSPRTLAG 975
            .:|.|:|...|..:..:...|.:.:.:....|....               .:|.|.||......
 Worm   551 VAHPNIVFYYGFSISGDEQALYLLFELMDTSLDKFI---------------DKSDAILSENERLD 600

  Fly   976 FALDIACGMEYIAGR--RIVHRDLAARNVLLDHNG------MCKICDFGMSIDLDAERMRKEQEK 1032
            ....|..||.::..|  .|||.|||||||||..:.      :|||.|.|::             |
 Worm   601 ILAQICRGMSFLHTRTPSIVHGDLAARNVLLKKHPVYIKKYICKITDLGLA-------------K 652

  Fly  1033 NAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALP 1097
            ...::|                                :.|.|.|                ..:|
 Worm   653 TCLDEL--------------------------------YTSYDDP----------------TKIP 669

  Fly  1098 IRWMAPESLQYHMFTTETDIWAFGIVLWEIATLGSTPYSQ-LTGREVIRRVPQGLRPDLPKESRH 1161
            .:|:.||.|.....:.:|||||||||.:|:......||.. :....:.:.:..|...:.......
 Worm   670 FKWLPPEVLGSRTLSLKTDIWAFGIVCFEVCDKVGEPYGACVPTSNLCQYLTDGYVHEKGLHMSD 734

  Fly  1162 EFYNLMSRCWHKEPHMRPSFAQ 1183
            ..||:...|..:.|..|||||:
 Worm   735 TIYNIALDCMRQHPIERPSFAE 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	82/357 (23%)
		PTKc	860..1187	CDD:270623	79/339 (23%)
W03A5.1	NP_498153.3	PTKc	498..761	CDD:270623	79/341 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000