Protein Alignment Tie and W04G5.10

DIOPT Version :9

• Sequence 1: NP_523928.1
• Gene: Tie / 38559
• FlyBaseID: FBgn0014073
• Length: 1233
• Species: Drosophila melanogaster
• Sequence 2: NP_492969.2
• Gene: W04G5.10 / 173049
• WormBaseID: WBGene00012270
• Length: 412
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 122/508 - (24%)
• Similarity: 195/508 - (38%)
• Gaps: 162/508 - (31%)

  Fly   722 MRRMNLVTLVLVAVGVIPLAAIILYLVRNFVIRRRAKQSEVFDV----------CITDQQPISPV 776
            |...||..:.:..:.|:...|:.|:|:  ::.||....|...|:          .:|...|||
 Worm     1 MMLRNLFPIFIYIIFVLLFLALSLFLL--YIWRRILTNSSNSDLGGSEEDVERSLLTTSLPIS-- 61

  Fly   777 KKVDSKYQVD----DDEDEVDHQHHQHMQHHQNHQNHQNHQHHQAMPMSQASQRDANHNRYGNND 837
                :||.:|    ..|.|:                           :|:..:
 Worm    62 ----NKYDLDRTRIQTESEL---------------------------ISETIK------------ 83

  Fly   838 DKTSLASEFH---DFERSNIRLKSLLGEGNFGQVWKAE--ADDLSGHFGATRIVAVK---TIRAC 894
               ||..:.|   |.|...|..::.:|.|.||.|::||  .:..:.:|   .|||||   .|...
 Worm    84 ---SLIGDNHLEIDPENLKISTENYIGSGFFGTVYRAELRRERRNSNF---MIVAVKEPSNIHNI 142

  Fly   895 SAQVSLKDEANIMRKLGSHQNVVTLLGACVESEPHMLIMEYAMRGRLLSLLRAARSATNILPASV 959
            ..:..|.:|.|:|..:..|.|:::|:|. |.....|::.||...|.||..||..:...:.:....
 Worm   143 RQKKILHEELNVMCSMEKHPNILSLVGV-VTQRNVMIVTEYVEDGDLLKFLRKCKFDKDSVKLDE 206

  Fly   960 PGGRSLAPLSPRTLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAE 1024
            ..      |....|..|...||.||:|:.....||||||.||||:.:||:.||.|||::
 Worm   207 KS------LCKADLFSFTFQIANGMQYLERVPCVHRDLALRNVLIKNNGVLKIADFGLA------ 259

  Fly  1025 RMRKEQEKNAANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDT 1089
                          .||                                      :||.::...|
 Worm   260 --------------RRH--------------------------------------DKKDYYRTKT 272

  Fly  1090 IGKRHALPIRWMAPESLQYH----MFTTETDIWAFGIVLWEIATLGSTPYSQLTGR--------- 1141
            ...  ||||:|:|||..:..    .|.:::|:|::|:.|:||.:||.:||::|...
 Worm   273 TDT--ALPIKWLAPECFEEEEEKIRFDSKSDVWSYGVCLYEIFSLGESPYNELDSNNFAFLQVLA 335

  Fly  1142 EVIRRVPQGLRPDLPKESRHEFYNLMSRCWHKEPHMRPSFAQ----SRLEITR 1190
            :.:|:   |.....|:....:.|..|..||:..|..||||..    ||.::.:
 Worm   336 DFLRK---GNTLSEPEHCAPKMYYFMKSCWNLIPEERPSFTACTNFSRTQLNQ 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	94/346 (27%)
		PTKc	860..1187	CDD:270623	95/348 (27%)
W04G5.10	NP_492969.2	PTKc	104..378	CDD:270623	93/346 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910