Sequence 1: | NP_523928.1 | Gene: | Tie / 38559 | FlyBaseID: | FBgn0014073 | Length: | 1233 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_034359.2 | Gene: | Flt3 / 14255 | MGIID: | 95559 | Length: | 1000 | Species: | Mus musculus |
Alignment Length: | 456 | Identity: | 123/456 - (26%) |
---|---|---|---|
Similarity: | 184/456 - (40%) | Gaps: | 148/456 - (32%) |
- Green bases have known domain annotations that are detailed below.
Fly 845 EFHDFE--------RSNIRLKSLLGEGNFGQVWKAEADDLSGHFGATRIVAVKTIR----ACSAQ 897
Fly 898 VSLKDEANIMRKLGSHQNVVTLLGACVESEPHMLIMEYAMRGRLLSLLRAARSA-----TNILP- 956
Fly 957 --------------ASVPGGR---------------------------------------SLAPL 968
Fly 969 SPRTLAGFALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKN 1033
Fly 1034 AANDLMRHNAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPI 1098
Fly 1099 RWMAPESLQYHMFTTETDIWAFGIVLWEIATLGSTPYSQL-TGREVIRRVPQGLRPDLPKESRHE 1162
Fly 1163 FYNLMSRCWHKEPHMRPSFAQSRLEITRSLHKWVDDDSAASD---YMDVSGFSEDLEHGVVYFNH 1224
Fly 1225 R 1225 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Tie | NP_523928.1 | TyrKc | 854..1183 | CDD:197581 | 109/392 (28%) |
PTKc | 860..1187 | CDD:270623 | 109/390 (28%) | ||
Flt3 | NP_034359.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 45..67 | ||
ig | 256..346 | CDD:278476 | |||
PKc_like | 573..950 | CDD:304357 | 115/426 (27%) | ||
Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of ligand binding. /evidence=ECO:0000250 | 592..598 | 1/3 (33%) | |||
Pkinase_Tyr | 611..946 | CDD:285015 | 110/405 (27%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 968..1000 | 4/9 (44%) | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR24416 |
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
2 | 2.000 |