DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tie and LOC100491469

DIOPT Version :9

Sequence 1:	NP_523928.1	Gene:	Tie / 38559	FlyBaseID:	FBgn0014073	Length:	1233	Species:	Drosophila melanogaster
Sequence 2:	XP_031750439.1	Gene:	LOC100491469 / 100491469	-ID:	-	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	289	Identity:	84/289 - (29%)
Similarity:	123/289 - (42%)	Gaps:	92/289 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   851 RSNIRLKSLLGEGNFGQVWKAEADDLSGHFGATRIVAVKTIRACSAQVS-LKDEANIMRKLGSHQ 914
            ||..:|...||.||||:||:       |.:.....||:||.:..:...| .|.|.|.::.| .|:
Frog   220 RSEFKLVRQLGAGNFGEVWE-------GLWNNKDKVAIKTFKQDNINESDFKKEVNALKTL-CHK 276

  Fly   915 NVVTLLGACVESEPHMLIMEYAMRGRLLSLLRAARSATNILPASVPGGRSLAPLSPRTLAGF--- 976
            |::.|...|...||..::.|...:|.||..||...            ||.|      |...|
Frog   277 NLIQLYAVCSVGEPVYIVTELMSKGSLLQFLRGTE------------GRHL------TAGSFMHI 323

  Fly   977 ALDIACGMEYIAGRRIVHRDLAARNVLLDHNGMCKICDFGMSIDLDAERMRKEQEKNAANDLMRH 1041
            ...:|.||.::....:|||||||||||:....:||:.|||::      |:.|:       ||
Frog   324 ISQVAEGMVFLEKEHVVHRDLAARNVLVGEKLVCKVADFGLA------RILKD-------DL--- 372

  Fly  1042 NAHKFKFDFGSRYILQHWQHTFGQGQGQGHCSKDQPHGEKKSHHGHDTIGKRHALPIRWMAPESL 1106
                        |.||                     |..|             :||:|.|||.|
Frog   373 ------------YSLQ---------------------GNIK-------------IPIKWTAPEVL 391

  Fly  1107 QYHMFTTETDIWAFGIVLWEIATLGSTPY 1135
            ...:::|::|:|::|||::|:..||..||
Frog   392 TRSIYSTKSDVWSYGIVMYEVYMLGQMPY 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581	82/286 (29%)
Tie	NP_523928.1	PTKc	860..1187	CDD:270623	81/280 (29%)
LOC100491469	XP_031750439.1	SH3_Srms	46..100	CDD:212780
		SH2	113..191	CDD:417686
		PKc_like	216..>422	CDD:419665	84/289 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D539311at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010