DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15021 and mmp24

DIOPT Version :9

Sequence 1:	NP_647902.1	Gene:	CG15021 / 38546	FlyBaseID:	FBgn0035544	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	XP_699803.4	Gene:	mmp24 / 571143	ZFINID:	ZDB-GENE-040724-262	Length:	606	Species:	Danio rerio

Alignment Length:	168	Identity:	41/168 - (24%)
Similarity:	51/168 - (30%)	Gaps:	65/168 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VALLLAAGVHADVSHLDTDLQEDGY--HYKQPSVPFPPPG--------------SGNGIEDS--- 53
            :.:..|:|.|.|.|..|   .|.|:  |     ..||.||              .||...|.
Zfish   180 IMIFFASGFHGDSSPFD---GEGGFLAH-----AYFPGPGIGGDTHFDSDEPWTLGNANHDGNDL 236

  Fly    54 ------------GIGPGPAPSA-PAPSYGPPQTR------------------PPP--PPPPPQPT 85
                        |:.....||| .||.|...:|.                  |..  .|..|.||
Zfish   237 FLVAVHELGHALGLEHSSDPSAIMAPFYQYMETHNFKLPLDDLQGIQKIYGIPTAMLEPTRPLPT 301

  Fly    86 PPAPRPSYGPP-----QTQPPRPPPQPTPSAPAPPPPS 118
            .||.||.....     |::|.||.....||:|....|:
Zfish   302 FPARRPHSTSERKHERQSRPGRPSAGDRPSSPGHGKPN 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15021	NP_647902.1	None
mmp24	XP_699803.4	PG_binding_1	41..94	CDD:279773
		Peptidase_M10	122..287	CDD:278824	24/114 (21%)
		ZnMc_MMP	122..287	CDD:239805	24/114 (21%)
		HX	338..530	CDD:238046	1/2 (50%)
		DUF3377	536..606	CDD:288690
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900