DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15021 and mmp14b

DIOPT Version :9

Sequence 1:	NP_647902.1	Gene:	CG15021 / 38546	FlyBaseID:	FBgn0035544	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_919395.1	Gene:	mmp14b / 566945	ZFINID:	ZDB-GENE-030901-2	Length:	621	Species:	Danio rerio

Alignment Length:	175	Identity:	44/175 - (25%)
Similarity:	48/175 - (27%)	Gaps:	69/175 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VALLLAAGVHADVSHLDTDLQEDGY--HYKQPSVPFPPPGSGNGIEDS----------------- 53
            :.|..|.|.|.|.|..|   .|.|:  |     ..||    ||||...
Zfish   170 IMLFFADGFHGDASPFD---GEGGFLAH-----AYFP----GNGIGGDTHFDAAEPWTIGNKDLL 222

  Fly    54 ----------------GIGPGPAPSA-PAPSYGPPQTRPPPPPPPPQPTPPAPRPSYGPPQTQPP 101
                            |:.....||| .||.|   |.........|.......:..|||.....|
Zfish   223 GNDVFLVAVHELGHALGMEHSNDPSAIMAPFY---QWMETDHFVLPDDDRKGIQKLYGPGSGGHP 284

  Fly   102 RPPPQPTPSAPAPPPPSYGPPQTPPPRPPPQPTPSAPAPPPSYGP 146
            |||..|                 ..|...|.|||..|. .|||||
Zfish   285 RPPVSP-----------------ETPHHTPYPTPYRPG-GPSYGP 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15021	NP_647902.1	None
mmp14b	NP_919395.1	PG_binding_1	29..81	CDD:279773
		Peptidase_M10	111..277	CDD:278824	25/121 (21%)
		ZnMc_MMP	111..277	CDD:239805	25/121 (21%)
		HX	311..503	CDD:238046	1/1 (100%)
		DUF3377	563..621	CDD:288690
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900