DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15021 and MMP16

DIOPT Version :9

Sequence 1:NP_647902.1 Gene:CG15021 / 38546 FlyBaseID:FBgn0035544 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_005932.2 Gene:MMP16 / 4325 HGNCID:7162 Length:607 Species:Homo sapiens


Alignment Length:170 Identity:42/170 - (24%)
Similarity:51/170 - (30%) Gaps:74/170 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 VALLLAAGVHADVSHLDTDLQEDGY--HYKQPSVPFPPPGSGN---------------------- 48
            :.::.|:|.|.|.|..|   .|.|:  |     ..||.||.|.                      
Human   184 ITIIFASGFHGDSSPFD---GEGGFLAH-----AYFPGPGIGGDTHFDSDEPWTLGNPNHDGNDL 240

  Fly    49 ------------GIEDSGIGPGPAPSA-PAP----------------------SYGPPQTRPPPP 78
                        |:|.|.     .|:| .||                      .||||...|||.
Human   241 FLVAVHELGHALGLEHSN-----DPTAIMAPFYQYMETDNFKLPNDDLQGIQKIYGPPDKIPPPT 300

  Fly    79 PPPPQPTPPAPRPSYGPPQTQPPRPPPQPT--PSAPAPPP 116
            .|.|...|....|...|.:...|:||..||  ||.|...|
Human   301 RPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAKP 340

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15021NP_647902.1 None
MMP16NP_005932.2 PG_binding_1 42..96 CDD:366659
Cysteine switch. /evidence=ECO:0000250 99..106
Peptidase_M10 126..291 CDD:334067 21/119 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 281..340 20/58 (34%)
PHA03247 <292..338 CDD:223021 18/45 (40%)
HX 340..532 CDD:238046 1/1 (100%)
Hemopexin 1 340..388 1/1 (100%)
Hemopexin 2 389..434
Hemopexin 3 436..484
Hemopexin 4 485..532
DUF3377 538..607 CDD:371766
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1565
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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