DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15021 and Mmp25

DIOPT Version :9

Sequence 1:NP_647902.1 Gene:CG15021 / 38546 FlyBaseID:FBgn0035544 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_001028511.1 Gene:Mmp25 / 240047 MGIID:2443938 Length:615 Species:Mus musculus


Alignment Length:305 Identity:75/305 - (24%)
Similarity:88/305 - (28%) Gaps:104/305 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   161 SAP----APSYGPPQPQPPAPQPPSPPSPQPGPEYLP------PDQPKPRPTPSRPQPPPPPPPR 215
            |||    .|.|     |.|...|.:...||...:.|.      ...|..||| .:|..|||.||.
Mouse   299 SAPNSIMRPFY-----QGPVGDPATYRLPQDDRDGLQQLYGRVSQNPNARPT-RKPLVPPPQPPA 357

  Fly   216 PQPTPGYGPPPPPPPPKPQPTPG-YGPPTPPPG-----PGP----AQPAPQPPRPQPP------R 264
            .       ||..|..|.|....| :.......|     .||    .||:.|...|:|.      .
Mouse   358 M-------PPDSPATPVPDRCEGNFDAVANIRGEIFLFKGPWFWRLQPSGQLVSPRPAGLHRFWE 415

  Fly   265 PQPPRPQP-GSEYLPPPGENEVTPTQPQ-----------PTAPVPEYGPPPPA--------PPAG 309
            ..|...:. .:.|..|.....:..:.||           ...|:.|:|.||..        |..|
Mouse   416 GLPTHVKVIQAAYARPLDGRIILFSGPQFWVFQERQLEGAARPLVEFGLPPGEDVDAVFSWPHNG 480

  Fly   310 PTYQPRPPAPPAPAPGPTYQPRPPAPPAPAPGPTYQPRPPS--PPAPPAP----------TY--- 359
            .||..|         |..|.........|.||   .||..|  ..||.||          ||   
Mouse   481 KTYLIR---------GQKYWRYDEVAARPDPG---YPRALSLWDGAPFAPDDVTISNTGDTYFFK 533

  Fly   360 -----------------QPQPPAPP-APAPGPTYQPRPPAPPAPT 386
                             .|||..|. ...|.|...||..:||..|
Mouse   534 GTHFWRFAEGSVKAESDSPQPIGPKWLDCPAPNSDPRVTSPPKTT 578

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15021NP_647902.1 None
Mmp25NP_001028511.1 PG_binding_1 89..140 CDD:279773
Cysteine switch. /evidence=ECO:0000250 143..150
Peptidase_M10 170..334 CDD:278824 11/39 (28%)
ZnMc_MMP 170..334 CDD:239805 11/39 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 336..366 13/37 (35%)
HX 368..562 CDD:238046 43/205 (21%)
Hemopexin 1 368..417 10/48 (21%)
Hemopexin 2 421..466 7/44 (16%)
Hemopexin 3 467..515 13/59 (22%)
Hemopexin 4 516..562 8/45 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 547..582 11/32 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1565
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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