DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15021 and Mmp9

DIOPT Version :9

Sequence 1:	NP_647902.1	Gene:	CG15021 / 38546	FlyBaseID:	FBgn0035544	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_038627.1	Gene:	Mmp9 / 17395	MGIID:	97011	Length:	730	Species:	Mus musculus

Alignment Length:	165	Identity:	53/165 - (32%)
Similarity:	60/165 - (36%)	Gaps:	50/165 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   273 GSEYL------PPPGENEVTPTQPQPTAPVPEYGP--PPPA-PPAGPTYQPRPPAPPAPAPGPTY 328
            |.:||      |.|.....|.|:|||||| |...|  ||.| |..|||..|    ..||:||||.
Mouse   438 GIQYLYGRGSKPDPRPPATTTTEPQPTAP-PTMCPTIPPTAYPTVGPTVGP----TGAPSPGPTS 497

  Fly   329 QPRPPAPPAPAPGPTYQPRPPSPPAPPAPTYQPQPPAPP-------------------------- 367
            .|.|....||:||||   .||:..:..|.|....|...|
Mouse   498 SPSPGPTGAPSPGPT---APPTAGSSEASTESLSPADNPCNVDVFDAIAEIQGALHFFKDGWYWK 559

  Fly   368 ------APAPGPTYQPRP-PAPPAPTPEYGPPPPT 395
                  :|..||....|. ||.||........|.|
Mouse   560 FLNHRGSPLQGPFLTARTWPALPATLDSAFEDPQT 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15021	NP_647902.1	None
Mmp9	NP_038627.1	PG_binding_1	41..95	CDD:279773
		Cysteine switch. /evidence=ECO:0000250\|UniProtKB:P14780	98..105
		Peptidase_M10	115..444	CDD:278824	3/5 (60%)
		ZnMc_MMP	115..444	CDD:239805	3/5 (60%)
		FN2	223..271	CDD:128373
		FN2	281..329	CDD:128373
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	442..529		39/94 (41%)
		PT	474..525	CDD:282710	25/57 (44%)
		HX	532..729	CDD:238046	11/63 (17%)
		Hemopexin 1	536..581		5/44 (11%)
		Hemopexin 2	582..626		4/13 (31%)
		Hemopexin 3	628..675
		Hemopexin 4	676..729
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900