Protein Alignment nAChRbeta1 and htr3b

DIOPT Version :9

• Sequence 1: NP_523927.2
• Gene: nAChRbeta1 / 38545
• FlyBaseID: FBgn0000038
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_021324909.1
• Gene: htr3b / 571632
• ZFINID: ZDB-GENE-071012-4
• Length: 369
• Species: Danio rerio
• Alignment Length: 386
• Identity: 106/386 - (27%)
• Similarity: 178/386 - (46%)
• Gaps: 58/386 - (15%)

  Fly     9 LLCSILVLVAFSLVSASEDEER-----LVRDLFRGYNKLIRPVQNMTQKVGVRFGLAFVQLINVN 68
            ||.|:|:.|........|..:|     |.|.|.|.||..:|||||.|:...:...|....:::|:
Zfish     5 LLLSLLLSVIPLAELVPEKPKRSALNQLTRLLLRKYNCGVRPVQNWTKPTTIYIDLIIQAVLDVD 69

  Fly    69 EKNQIMKSNVWLRLVWYDYQLQWDEADYGGIGVLRLPPDKVWKPDIVLFNNADGNYEVRYKSNVL 133
            .:.|.:.:::|.|.:|.|..|.||..::.||..:.|..|.:|.||:::....|..     ||.|:
Zfish    70 GQTQKVTTSIWYRQIWNDEFLVWDPDEFDGITEISLSSDAIWVPDLIISEFVDVG-----KSPVI 129

  Fly   134 IYP----TGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLALYNNKNFV--D 192
            .|.    :|:|....|....|:|.:::..||||:|.|.:.|.||..:..:|.|||:.....:  |
Zfish   130 PYVYVNCSGKVKNYKPIQVVSACHLEIYAFPFDKQNCTLTFRSWLHSVSEVDLALWRPAEEIAND 194

  Fly   193 LSDYWKSGTWDIIEVPA---YLNVYEGDSNHPTETDITFYIIIRRKTLFYTVNLILPTVLISFLC 254
            ..::...|.|:::.||:   .||:.:.|     ...|.|.::|||:.|.|.|.|::|::.:..:.
Zfish   195 TREFMNDGEWELLGVPSRYWTLNLEDRD-----YAQIQFNVLIRRRPLLYVVGLLIPSIFLMVVD 254

  Fly   255 VLVFYLPAEAGEKVTLGISILLSLVVFLLLVSKILPPTSLVLPLIAKYLLFTFIMNTVSILVTVI 319
            |:.||||..:|.::|...||||...|..:.:...:|.|::..|||..:......:..:|:.:::.
Zfish   255 VISFYLPPNSGTRITFKTSILLGYTVIRVNLMDEIPATAIKTPLIGVFFAICMALLLLSLAMSIF 319

  Fly   320 IINWNFRGPRTHRMPMYIRSIFLHYLPAFLFMKRPRKTRLRWMMEMPGMSMPAHPHPSYGS 380
            ::.                  .|||..                .|:..|||.|.....|||
Zfish   320 VVK------------------LLHYSE----------------KEVKEMSMSACLLDKYGS 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta1	NP_523927.2	LIC	8..500	CDD:273305	106/386 (27%)
		Neur_chan_LBD	28..236	CDD:280998	66/221 (30%)
		Neur_chan_memb	243..498	CDD:280999	31/138 (22%)
htr3b	XP_021324909.1	Neur_chan_LBD	26..>325	CDD:332142	89/326 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910