Protein Alignment nAChRbeta1 and CG12344

DIOPT Version :9

• Sequence 1: NP_523927.2
• Gene: nAChRbeta1 / 38545
• FlyBaseID: FBgn0000038
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Alignment Length: 352
• Identity: 78/352 - (22%)
• Similarity: 153/352 - (43%)
• Gaps: 41/352 - (11%)

  Fly    17 VAFSLVSASEDEE---------RLVRDLFRGYNKLIRPVQNMTQKVGVRFGLAFVQLINVNEKNQ 72
            :.|.|:..||..|         |:|  |...|.|.|||.......|.|.|.:..|.:.::|.::.
  Fly    15 LGFILMWLSEATEAHMNYTAKPRVV--LPPNYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDM 77

  Fly    73 IMKSNVWLRLVWYDYQLQ-----WDEA-DYGGIGVLRLPP--DKVWKPDIVLFNNADGNY-EVRY 128
            ..:.::::...|.:.:|:     ::|. ||    |..||.  :..|:||....|:..... .:.:
  Fly    78 DFRVDMFIHQRWLESRLEIPDDIFEEGDDY----VTLLPEVFENFWQPDPYFLNSKIAEIATLTH 138

  Fly   129 K-SNVLIYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLALYNNKNFVD 192
            | ::|.:|....|.:........:|.::...:|.|.|.|.:...|::.|..:|.|..  :.:.|.
  Fly   139 KFTSVTLYKNKTVRYAARMHAIIACQMEFQLYPMDIQVCPIYIESFSSNNQKVKLRW--SDSGVT 201

  Fly   193 LSDYWKSGTWDIIEVPAYLNVYEGDSNHPTE----TDITFYIIIRRKTLFYTVNLILPTVLISFL 253
            |:...|...:::.:.   |.:.|.|...|.:    :.:|.|....|:...:.:....|:.|:..|
  Fly   202 LNPELKLLQYNLGQP---LELEESDGYMPEKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVML 263

  Fly   254 CVLVFYLPAEA-GEKVTLGISILLSLVVFLLLVSKILPPTSLVLPL---IAKYLLFTFIMNTVSI 314
            ....|:|..:| ..:|||.::.:|:||.  :.....:||.:.|..|   :|..:|..|......:
  Fly   264 SWFSFWLGLDAIPGRVTLLVTCMLTLVT--MFTGADIPPVAYVKALDLWMAGCMLSVFAALAEFV 326

  Fly   315 LVTVIIINWNFRGPRTHR-MPMYIRSI 340
            :|.|:.:.:.::..|..: :||.|.::
  Fly   327 VVKVLDVQYQYQVNRIPKVLPMRISNM 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta1	NP_523927.2	LIC	8..500	CDD:273305	78/352 (22%)
		Neur_chan_LBD	28..236	CDD:280998	49/230 (21%)
		Neur_chan_memb	243..498	CDD:280999	25/103 (24%)
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	78/352 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100