Protein Alignment nAChRbeta1 and CG8916

DIOPT Version :9

• Sequence 1: NP_523927.2
• Gene: nAChRbeta1 / 38545
• FlyBaseID: FBgn0000038
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_573090.3
• Gene: CG8916 / 32553
• FlyBaseID: FBgn0030707
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 452
• Identity: 93/452 - (20%)
• Similarity: 172/452 - (38%)
• Gaps: 112/452 - (24%)

  Fly    25 SEDEERLVRDLFRGYNKLIRPVQNMTQKVGVRFGLAFVQLINVNEKNQIMKSNVWLRLVWYDYQL 89
            |.:...::.:|.:.|.:...|.........|:..:....:..|:|.:.....:.:.|..|.|.:|
  Fly   105 SRNISMILENLLKRYEQSQLPTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRL 169

  Fly    90 QWDEADYGGIGVLRLP---PDKVWKPDIVLFNNADGNYEVRYKSNVLIY--PTGEVLWVPPAIYQ 149
            .:.    |.|..|.|.   .||:|:||...:|.......:....|.|:.  ..|.:|:......:
  Fly   170 SFK----GPIKSLSLSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIK 230

  Fly   150 SSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSLALYNNKNFVDLSDYWKSGT---WDIIEVPAYL 211
            ::|.:::..||.|:|:|.:..||:.:...|:   :|..||..|...:....|   :|:|.:
  Fly   231 ATCPMELQNFPMDRQSCPLVIGSYGYINQQL---IYEWKNQDDAVSFVPGMTLNQFDLISM---- 288

  Fly   212 NVYEGDSNHPTETDITFYII---IRRKTLFYTVNLILPTVLISFLCVLVFYLPAEA-GEKVTLGI 272
             ::...:....|.|.:...:   ::|.|.::.:.:.:|.:||..|..:.|::..|| .::|:|.:
  Fly   289 -MHRNFTTVRREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCV 352

  Fly   273 SILLSLVVFLLLVSKILPPTSLVLPLIAKYLLFTFIMNTVSILVTVIIINWNFRGPRTHRMPMYI 337
            :.:|:|       |.|...:...||.: ||               ...::|
  Fly   353 TSVLTL-------STISLDSRTDLPKV-KY---------------ATALDW-------------- 380

  Fly   338 RSIFLHYLPAFLFMKRPRKTRLRWMMEMPGMSMPAHPHPSYGSPAELPKHISAIGGKQSKMEVME 402
               ||  |.:||:.       :..::|..|:    |.....|| .|.|                :
  Fly   381 ---FL--LMSFLYC-------IATLLEFAGV----HYFTKLGS-GESP----------------Q 412

  Fly   403 LSDLHHPNCKINRKVNSGGELGLGDG-----------CRRESESSDSILLSPEASKATEAVE 453
            |.|.....|..|...:..||:. |||           ....||:.|:     ||. |:|:||
  Fly   413 LEDQWEDICIANSLSDHAGEVD-GDGEADADPFADEDSSNGSENDDN-----EAG-ASESVE 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta1	NP_523927.2	LIC	8..500	CDD:273305	93/452 (21%)
		Neur_chan_LBD	28..236	CDD:280998	43/218 (20%)
		Neur_chan_memb	243..498	CDD:280999	48/223 (22%)
CG8916	NP_573090.3	LIC	92..598	CDD:273305	93/452 (21%)
		Neur_chan_LBD	111..315	CDD:280998	43/215 (20%)
		Neur_chan_memb	322..>403	CDD:280999	26/133 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100