Protein Alignment nAChRbeta1 and lgc-9

DIOPT Version :9

• Sequence 1: NP_523927.2
• Gene: nAChRbeta1 / 38545
• FlyBaseID: FBgn0000038
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: NP_500341.1
• Gene: lgc-9 / 182195
• WormBaseID: WBGene00015412
• Length: 464
• Species: Caenorhabditis elegans
• Alignment Length: 365
• Identity: 85/365 - (23%)
• Similarity: 164/365 - (44%)
• Gaps: 44/365 - (12%)

  Fly    10 LCSILVLVAFSLVSAS-----------EDE------ERLVRDLFRGYNKLIRPVQNMTQKVGVRF 57
            |.|:|:.:....:.:|           ||:      ..|:..:.|.|:|.:||.....:.|.|..
 Worm     6 LLSVLISMKVGHIRSSRLLQHSQHGHYEDDYIKTEPTHLIETIQRRYDKRVRPFAESNRPVIVHM 70

  Fly    58 GLAFVQLINVNEKNQIMKSNVWLRLVWYDYQLQWDEADYGGIGVLRLPPDKVWKPDIVLFNN--- 119
            .:....|..|.|..|:....:.....|.|.:|.|:.||:.|:..:.:|...||.|.:.::|:
 Worm    71 TIVLGILTEVRENQQVASFVISHVQKWRDPKLAWNPADHSGLTQVVMPRSLVWVPKLFIYNSMDT 135

  Fly   120 ----ADGNYEVRYKSNVLIYPTGEVLWVPPAIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQV 180
                .|..|:||      |..||.|....|....:.|.|::..||||.|.|.:...|...:.:::
 Worm   136 KDMLTDDRYDVR------IQHTGHVKVNSPQFVSTLCRINIDLFPFDTQFCAIALASPLLSVEEM 194

  Fly   181 SLALYNNKNFVDLSDYWK-SGTWDIIEVPAYLNVYEGDSNHPTETDITFYIIIRRKTLFYTVNLI 244
            .:    |.....:..|:. :..|.::.|......:..:..:..|  :.:.:.:.|:..:|...::
 Worm   195 DV----NATQPPVDSYFSGNAEWQVMNVTVKQMKFMEEGEYRAE--VHYILHLNRRPTYYITVIV 253

  Fly   245 LPTVLISFLCVLVFYLPAE----AGEKVTLGISILLSLVVFLLLVSKILPPTSLVLPLIAKYLLF 305
            :||.|||.|.:|..:.|..    ..|||:||:..||::.|.|.:|:..:|.:. .:||:..|::.
 Worm   254 VPTFLISALSILGIFSPGSNDGPRNEKVSLGLGSLLAMTVLLDIVAGAMPKSD-AIPLLGYYIML 317

  Fly   306 TFIMNTVSILVTVIIINWNFRGPRTHRM--PMYIRSIFLH 343
            ..::..:.:.|::.:::.:....:|.:|  |.|.|.:||:
 Worm   318 VILLCAIGVAVSMAMLSMSRSCIQTSKMPPPHYYRLLFLN 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta1	NP_523927.2	LIC	8..500	CDD:273305	85/365 (23%)
		Neur_chan_LBD	28..236	CDD:280998	48/221 (22%)
		Neur_chan_memb	243..498	CDD:280999	30/107 (28%)
lgc-9	NP_500341.1	Neur_chan_LBD	42..245	CDD:280998	48/214 (22%)
		Neur_chan_memb	252..>347	CDD:280999	25/95 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810