Protein Alignment nAChRbeta1 and LOC110439304

DIOPT Version :10

• Sequence 1: NP_523927.2
• Gene: nAChRbeta1 / 38545
• FlyBaseID: FBgn0000038
• Length: 521
• Species: Drosophila melanogaster
• Sequence 2: XP_073801280.1
• Gene: LOC110439304 / 110439304
• -ID: -
• Length: 424
• Species: Danio rerio
• Alignment Length: 317
• Identity: 73/317 - (23%)
• Similarity: 139/317 - (43%)
• Gaps: 45/317 - (14%)

  Fly    21 LVSASEDEERLVRDLFRGYNKLIRPVQNMTQKVGVRFGLAFVQLINVNEKNQIMKSNVWLRLVWY 85
            :::.:..:|...|....||...:.....:|            .:..||||.|.:.:.|.:...||
Zfish    59 ILNFTNSKETYKRPFIDGYPSFVFVDMYVT------------SIAAVNEKAQSLSTQVKMMTAWY 111

  Fly    86 DYQLQWDEADYGGIGVLRLPPDKVWKPDIVLFNNADGNYEVRYKSNVLIYPTGEVLW-----VPP 145
            :....|..:...||...:...:..|.|||::..:...:|.......|.:.     :|     :..
Zfish   112 NGIPLWMYSKQCGITRFQASKEMFWTPDILIKESIKTDYGTTPSPYVQLQ-----MWEFSVSIDI 171

  Fly   146 AIYQSSCTIDVTYFPFDQQTCIMKFGSWTFNGDQVSL--------ALYNNKNFVDLSDYWKSGTW 202
            ....::|.:|:..||||.|.|.:.|.|......::::        ...::||.:.     ..|.|
Zfish   172 LTLTTACRMDLYKFPFDTQICNITFQSAVHTNKELTIDPLSKAQNITQDSKNLLA-----AQGEW 231

  Fly   203 DIIEV---PAYLNVYEGDSNHPTETDITFY-IIIRRKTLFYTVNLILPTVLISFLCVLVFYLPAE 263
            :::.:   .|:..|. ||..     |:..| |.|:|:.|.|.:|:|:|......|.|..|::.|:
Zfish   232 ELLLINTSKAHATVL-GDLQ-----DVLVYQITIKRRPLLYVINIIIPVFFFIVLDVASFFIEAD 290

  Fly   264 AGEKVTLGISILLSLVVFLLLVSKILPPTSLVLPLIAKYLLFTFIMNTVSILVTVII 320
            ..:|::..:::||::.|.||:::..||.|:..:|||..|....|.:..:|||.|:::
Zfish   291 GADKLSFKVTLLLAISVLLLMLNDTLPSTADRIPLIGVYCSVIFSLIGISILETILV 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRbeta1	NP_523927.2	LIC	8..500	CDD:455710	73/317 (23%)
		LGIC_ECD_nAChR_proto_beta-like	27..236	CDD:349833	46/225 (20%)
		Cys-loop	152..166	CDD:349833	7/13 (54%)
LOC110439304	XP_073801280.1	None