DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15019 and LLPH

DIOPT Version :9

Sequence 1:	NP_001097502.1	Gene:	CG15019 / 38542	FlyBaseID:	FBgn0035541	Length:	146	Species:	Drosophila melanogaster
Sequence 2:	NP_115714.1	Gene:	LLPH / 84298	HGNCID:	28229	Length:	129	Species:	Homo sapiens

Alignment Length:	142	Identity:	45/142 - (31%)
Similarity:	71/142 - (50%)	Gaps:	22/142 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGRNNRSRKRRDEMNKIKKARYEAKELIRLKKTLGLLDADGNEIMKDISDVVEIKTAKELKREAK 65
            |.::.||:.:| :|...|:.:...||..|||..|.|   ||:.:|||:.::..:...|  .:..:
Human     1 MAKSLRSKWKR-KMRAEKRKKNAPKEASRLKSILKL---DGDVLMKDVQEIATVVVPK--PKHCQ 59

  Fly    66 SKEEQELIYEHQESLEKGEKVKVTNENTGVEHIFNSKTLKDQYGNYPAWF----KKKKTAKRLRK 126
            .|.:.|:         |.||..:..| |.::.  |.|||.||:|.||.|.    :|:..|||.::
Human    60 EKMQCEV---------KDEKDDMKME-TDIKR--NKKTLLDQHGQYPIWMNQRQRKRLKAKREKR 112

  Fly   127 KQHSQKKNFKQA 138
            |..|:.|..|.|
Human   113 KGKSKAKAVKVA 124

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15019	NP_001097502.1	Laps	3..135	CDD:287178	42/135 (31%)
LLPH	NP_115714.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27		8/26 (31%)
		Laps	3..117	CDD:370850	40/131 (31%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	100..129		9/25 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4811
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1594400at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR34253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.880