DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syx17 and stx17

DIOPT Version :9

Sequence 1:	NP_001261414.1	Gene:	Syx17 / 38541	FlyBaseID:	FBgn0035540	Length:	346	Species:	Drosophila melanogaster
Sequence 2:	XP_005158110.1	Gene:	stx17 / 492808	ZFINID:	ZDB-GENE-041114-164	Length:	292	Species:	Danio rerio

Alignment Length:	284	Identity:	87/284 - (30%)
Similarity:	142/284 - (50%)	Gaps:	32/284 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTRDE--KLPLKQAEVSIQRFQDVAVPHHLSLLKNHRSNIEKSLALGDWQKIKKEELNAMRVIKQ 63
            |..||  ||||::.|..||:|..||:|..|..|..|:.||||......|.|:..|.:|:.|.::|
Zfish     1 MMADEAGKLPLRRLEPPIQKFIKVAIPTDLERLHQHQHNIEKFQRNRQWDKLHHEHINSSRTVQQ 65

  Fly    64 IKNLLLEMDALREKVREEDLERFDDLMKPGRDTAFAGMKEFAELQ------------LKSPTSTL 116
            :::.|.||:.|..:||..|.|..:.|::|.||.|.|.::||.::.            :.:...|.
Zfish    66 LRSNLREMEKLCGRVRSVDAEALEKLVQPIRDRASAAIQEFLQIHSDAVNRQNFNEAIATVAETS 130

  Fly   117 SSQYDDDLDNQPQEVDMNSLPAHRHMPQLQLNFQLEEHQLAQRQACLDQMENLQQEIYDLHGMFQ 181
            .|:.|..:...|.......||                 ::...|...:..::|.:::..|:|:..
Zfish   131 HSEDDTGVSGSPVTQTQLLLP-----------------EIPSEQNAAESWDSLAEDLLQLNGLVN 178

  Fly   182 GMRQLTAEQSVAVEKIADNAEEALENVQQGELNLRRALTYKKAMYPVVGALLGTCVGGPIGLVAG 246
            ....:...|...::.|..|...|..||::|..:|.:|...|.|:.||.||::|..:|||:||:||
Zfish   179 EFSTIVHAQQEKIDSIEANVSIAAANVEEGTQSLGKAARAKLAVLPVAGAVVGGVLGGPLGLLAG 243

  Fly   247 MKAGGLAAV-GCGILGFTGGSVLK 269
            .|..|:||. |.|:|||.||::::
Zfish   244 FKVAGVAAAFGGGLLGFAGGNLIQ 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx17	NP_001261414.1	SNARE_syntaxin17	156..217	CDD:277199	12/60 (20%)
stx17	XP_005158110.1	SNARE_syntaxin17	153..214	CDD:277199	12/60 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579721
Domainoid	1	1.000	138	1.000	Domainoid score	I4840
eggNOG	1	0.900	-	-		E1_COG5325
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9917
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4517
OMA	1	1.010	-	-		QHG49838
OrthoDB	1	1.010	-	-		D1493840at2759
OrthoFinder	1	1.000	-	-		FOG0008362
OrthoInspector	1	1.000	-	-		oto40693
orthoMCL	1	0.900	-	-		OOG6_108277
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5748
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.700