DRSC/TRiP Functional Genomics Resources

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Protein Alignment slow and Svep1

DIOPT Version :10

Sequence 1:NP_647898.3 Gene:slow / 38540 FlyBaseID:FBgn0035539 Length:512 Species:Drosophila melanogaster
Sequence 2:NP_073725.2 Gene:Svep1 / 64817 MGIID:1928849 Length:3567 Species:Mus musculus


Alignment Length:144 Identity:41/144 - (28%)
Similarity:58/144 - (40%) Gaps:40/144 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   268 TWKHVATPCQ-----PPTFSGQKCTRVQVVH-EQAYRDVIDHKTAQQMTYDCCTGWSRENPRSDS 326
            ||.|....|:     ||:            | |.|....:.::....:||.|.:|:..|......
Mouse  3399 TWTHTNARCEKISCGPPS------------HVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSV 3451

  Fly   327 CMK-------PICSA----RCQNGGNCTAPSTCSCPTGFTGRFCEQDVDECQTEKPCDQQCIN-- 378
            |::       |:|.|    .|||||.|..|:.||||.|:.||.||:.:        |...|:|  
Mouse  3452 CLENGTWTPSPVCRAVCRFPCQNGGVCQRPNACSCPDGWMGRLCEEPI--------CILPCLNGG 3508

  Fly   379 -THGSYFCRCRQGF 391
             ....|.|.|..|:
Mouse  3509 RCVAPYQCDCPTGW 3522

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slowNP_647898.3 EMI 245..319 CDD:462204 13/56 (23%)
EGF_CA <336..360 CDD:238011 14/23 (61%)
EGF_CA 362..401 CDD:214542 7/33 (21%)
Svep1NP_073725.2 VWA 84..259 CDD:459670
Ephrin_rec_like 311..361 CDD:429604
CCP 379..435 CDD:153056
CCP 439..495 CDD:153056
CCP <514..556 CDD:153056
HYR 560..642 CDD:460572
HYR 644..722 CDD:460572
Ephrin_rec_like 1004..1051 CDD:429604
Ephrin_rec_like 1058..1105 CDD:429604
Ephrin_rec_like 1112..1159 CDD:429604
EGF_CA 1195..1228 CDD:238011
EGF_CA 1230..1266 CDD:238011
EGF_CA 1268..1304 CDD:238011
EGF_CA 1306..1342 CDD:238011
EGF_CA 1344..1380 CDD:238011
EGF_CA 1382..1418 CDD:238011
PTX 1423..1621 CDD:238086
PHA02927 1643..1899 CDD:222943
EGF_3 1748..1782 CDD:463759
PHA02817 1899..>2008 CDD:165167
PHA02927 1957..2198 CDD:222943
PHA02927 2093..2318 CDD:222943
PHA02831 2277..>2435 CDD:165176
PHA02927 2400..2608 CDD:222943
Important for the interaction with integrin ITGA9:ITGB1. /evidence=ECO:0000269|PubMed:22654117 2638..2645
CCP <2670..2710 CDD:153056
PHA02927 2709..2941 CDD:222943
PHA02927 2903..3113 CDD:222943
PHA02927 3012..3225 CDD:222943
PHA02927 3232..3464 CDD:222943 16/76 (21%)
Blue background indicates that the domain is not in the aligned region.

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