Protein Alignment slow and EGFL7

DIOPT Version :9

• Sequence 1: NP_647898.3
• Gene: slow / 38540
• FlyBaseID: FBgn0035539
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_057299.1
• Gene: EGFL7 / 51162
• HGNCID: 20594
• Length: 273
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 73/250 - (29%)
• Similarity: 117/250 - (46%)
• Gaps: 36/250 - (14%)

  Fly   245 RHICMQQRTVTMPVKRTEVYSRPTWKHVATPCQPPTFSGQKCTRVQVVHEQAYRDVIDHKTAQQM 309
            |.:| ..|....||  :|.:.:..::...|.|.    ..:.|:..:.::..|||.......|:.
Human    28 RRVC-AVRAHGDPV--SESFVQRVYQPFLTTCD----GHRACSTYRTIYRTAYRRSPGLAPARP- 84

  Fly   310 TYDCCTGWSRENPRSDSCMKPICSARCQNGGNCTAPSTCSCPTGFTGRFCEQDVDECQTEK-PCD 373
            .|.||.||.|.:....:|...||...|:|||:|..|..|.||.|:.|..|:.|||||...: .|.
Human    85 RYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGGCP 149

  Fly   374 QQCINTHGSYFCRCRQGFVLQSDQQSC------KKVS---TNADDAF--EARDLENDIDDTDAEV 427
            |:|:||.|||:|:|.:|..|.:|...|      .:|:   |..|.|.  |.:.|::.:|..:.::
Human   150 QRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKL 214

  Fly   428 ATRLQKIEKSLANERVHTNELQKSLQATYSV----------VDTLKSRLSTLEKQ 472
            ...|..:. |||::     .|:..|....|:          :|:|..::|.||:|
Human   215 QLVLAPLH-SLASQ-----ALEHGLPDPGSLLVHSFQQLGRIDSLSEQISFLEEQ 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slow	NP_647898.3	EMI	246..318	CDD:284877	16/71 (23%)
		EGF_CA	<336..360	CDD:238011	11/23 (48%)
		EGF_CA	362..401	CDD:214542	19/45 (42%)
EGFL7	NP_057299.1	EMI	29..93	CDD:369419	16/71 (23%)
		EGF_CA	<110..135	CDD:238011	11/24 (46%)
		Cell attachment site	130..132		0/1 (0%)
		FXa_inhibition	141..176	CDD:373209	14/34 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BEDX
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H9427
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7458
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001719
OrthoInspector	1	1.000	-	-		otm42111
orthoMCL	1	0.900	-	-		OOG6_109468
Panther	1	1.100	-	-	LDO	PTHR14949
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.720