DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slow and egas-4

DIOPT Version :9

Sequence 1:	NP_647898.3	Gene:	slow / 38540	FlyBaseID:	FBgn0035539	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_501207.2	Gene:	egas-4 / 3564809	WormBaseID:	WBGene00018906	Length:	883	Species:	Caenorhabditis elegans

Alignment Length:	211	Identity:	52/211 - (24%)
Similarity:	87/211 - (41%)	Gaps:	60/211 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 CQNGGNCT----APST--CSCPTGFTGRFCEQDVDE-------CQTEKPCDQQCINTHGSYFCRC 387
            |:|||.|.    .|::  |:|...:||..|..||||       |:|:.| |..|:||:|||:|.|
Worm   450 CENGGECEDIIGPPNSYNCTCTPQWTGFNCTIDVDECVEDTTLCKTKDP-DATCVNTNGSYYCVC 513

  Fly   388 RQGFVLQSDQQSC--KKVSTNADDAFEARDLENDIDDTDAEVATRLQKIEKSLANERVHTNELQK 450
            .....    .:||  .|:.....:|... ||..|          :|.::.:.|.|:.....::..
Worm   514 SPNMF----GKSCLFNKIIYQILNATYG-DLGPD----------KLDEMAQELTNDPTLVRDIVP 563

  Fly   451 SLQATYSVVDTLKSRLS----------TLEKQAQDVSR--LQTN---------------LYKTES 488
            .|...||:  .:::.||          ..|:|..|::.  :|.|               .:|.|:
Worm   564 FLIGGYSL--EVRTSLSWTAADMFLWVAYEQQLIDLNSNFVQWNDKVLGNCFTFNHMNSSFKYEA 626

  Fly   489 RTNKLEGMLNLLLKCR 504
            |::...|.|.:.:..:
Worm   627 RSSGYPGGLEMQMNVK 642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slow	NP_647898.3	EMI	246..318	CDD:284877
		EGF_CA	<336..360	CDD:238011	10/29 (34%)
		EGF_CA	362..401	CDD:214542	18/47 (38%)
egas-4	NP_501207.2	EGF	101..131	CDD:278437
		EGF_CA	482..522	CDD:238011	16/44 (36%)
		ASC	<610..869	CDD:279230	5/33 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7458
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860