Protein Alignment slow and MEGF6

DIOPT Version :10

• Sequence 1: NP_647898.3
• Gene: slow / 38540
• FlyBaseID: FBgn0035539
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: XP_011539188.1
• Gene: MEGF6 / 1953
• HGNCID: 3232
• Length: 1560
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 85/284 - (29%)
• Similarity: 116/284 - (40%)
• Gaps: 80/284 - (28%)

  Fly   168 PSVTVTTAPPPNLNRRSASPG-------------SRSSIGTI---PPLVPARRGY-----SYTTT 211
            |.:.| :|.....|..:.||.             .:|..|.:   .|..|||..|     ||.|:
Human    22 PEIPV-SARSSRWNMEAVSPARVPTASTGVRNGPEKSGQGNVFLARPARPARGTYRRVSPSYLTS 85

  Fly   212 ------TSSPPVNTITTDNPFETNTIGRG----YPTDPKEME-----RRHICMQQRTVTMPVKRT 261
                  .|||..|             |||    :|....|.|     ||..|:|..:.|:||
Human    86 GDLEVQVSSPVRN-------------GRGSNRCWPHVCAEQELTLVGRRQPCVQALSHTVPV--- 134

  Fly   262 EVYSRPTWKHVATPCQPPTFSGQKCTRV----QVVHEQAYRDVIDHKTAQQMTYDCCTGWSRENP 322
                   ||   ..|      |.:...|    :.|:...||.|  :.|..:....||.||.:: |
Human   135 -------WK---AGC------GWQAWCVGHERRTVYYMGYRQV--YTTEARTVLRCCRGWMQQ-P 180

  Fly   323 RSDSCMKPICSAR-CQNGGNCTAPST--CSCPTGFTGRFCEQDVDECQTEK-PCDQQCINTHGSY 383
            ..:.|:...|||. |.:||.|...|.  |.||.||.|..|:.|||||:|.. .|..:|:||.|||
Human   181 DEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSY 245

  Fly   384 FCRCRQGFVLQSDQQSCKKVSTNA 407
            .|.|:.||.|.:|.::|..:::.|
Human   246 LCECKPGFRLHTDSRTCLAINSCA 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slow	NP_647898.3	EMI	245..319	CDD:462204	20/77 (26%)
		EGF_CA	<336..360	CDD:238011	11/25 (44%)
		EGF_CA	362..401	CDD:214542	19/39 (49%)
MEGF6	XP_011539188.1	EMI	107..176	CDD:462204	22/89 (25%)
		vWFA	<215..261	CDD:469594	22/45 (49%)
		FXa_inhibition	268..304	CDD:464251	1/2 (50%)
		vWFA	<342..384	CDD:469594
		FXa_inhibition	397..432	CDD:464251
		vWFA	<472..511	CDD:469594