DRSC/TRiP Functional Genomics Resources

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Protein Alignment DopEcR and Gpr52

DIOPT Version :9

Sequence 1:NP_001014559.1 Gene:DopEcR / 38539 FlyBaseID:FBgn0035538 Length:322 Species:Drosophila melanogaster
Sequence 2:NP_001139802.1 Gene:Gpr52 / 620246 MGIID:3643278 Length:361 Species:Mus musculus


Alignment Length:300 Identity:82/300 - (27%)
Similarity:143/300 - (47%) Gaps:19/300 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 KAVLISILGVAIVLSNLLIIATYANFKGPT---EVINYYLLSLAIADLLCGL--LVVPFSVYPAL 77
            :.|:|.:|...|:..||.:|..:  ...|.   ...:|::.::|.||||.|:  ||...|:....
Mouse    43 ETVVIVLLTFLIISGNLTVIFVF--HCAPLLHHYTTSYFIQTMAYADLLVGVTCLVPTLSLLHYS 105

  Fly    78 TGEWMYGDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLRYETVQTKTRCQCWMVFTWIS 142
            ||  ::..:.|:..||:...|.:||:.....||||||||:.|||.|..:.|..|.:..::..||.
Mouse   106 TG--VHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIIMIWIY 168

  Fly   143 AALLCCPPILGYSMP-IENNMTHICMLDWGNMAAYSATLAILVLGPSLISIVHNYGYIFVMMRK- 205
            :.|:..|...|:..| ...::...|...|...|.::..:..|:..|:.:.:...|.:||.:.|: 
Mouse   169 SCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTCFIVCLLYAPAALVVCFTYFHIFKICRQH 233

  Fly   206 ------IRSGEPIHDKEYATALAENLSNPSHMMSFALVFAFWVSWLPWILLRLYEVVTGDVIQST 264
                  .|:..|.|:.|.:.....:......|:.|.:...|::.|||:|:..|.|  :..|:.:.
Mouse   234 TKEINDRRARFPSHEVEASREAGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLE--SSRVLDNP 296

  Fly   265 LINFAVVWIGILNSFWKILIMTSMSPQFRIALRVFCLTIC 304
            .::|...|:.|.|||...:|.:..:..||:.||....|:|
Mouse   297 TLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMC 336

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DopEcRNP_001014559.1 7tm_classA_rhodopsin-like 18..289 CDD:410626 76/283 (27%)
TM helix 1 18..42 CDD:410626 7/23 (30%)
TM helix 2 51..73 CDD:410626 9/23 (39%)
TM helix 3 89..111 CDD:410626 6/21 (29%)
TM helix 4 134..150 CDD:410626 3/15 (20%)
TM helix 5 174..197 CDD:410626 3/22 (14%)
TM helix 6 230..252 CDD:410626 7/21 (33%)
TM helix 7 264..289 CDD:410626 7/24 (29%)
Gpr52NP_001139802.1 7tm_classA_rhodopsin-like 43..321 CDD:381740 76/283 (27%)
TM helix 1 43..68 CDD:381740 7/26 (27%)
TM helix 2 76..102 CDD:381740 10/25 (40%)
TM helix 3 114..144 CDD:381740 14/29 (48%)
TM helix 4 157..176 CDD:381740 4/18 (22%)
TM helix 5 200..225 CDD:381740 4/24 (17%)
TM helix 6 258..288 CDD:381740 8/29 (28%)
TM helix 7 296..321 CDD:381740 7/24 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 104 1.000 Domainoid score I6694
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 1 1.000 - - H74561
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0003993
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X5013
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.910

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