Protein Alignment DopEcR and Taar7c

DIOPT Version :10

• Sequence 1: NP_647897.2
• Gene: DopEcR / 38539
• FlyBaseID: FBgn0035538
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_001009975.1
• Gene: Taar7c / 494535
• RGDID: 1359258
• Length: 358
• Species: Rattus norvegicus
• Alignment Length: 319
• Identity: 82/319 - (25%)
• Similarity: 141/319 - (44%)
• Gaps: 62/319 - (19%)

  Fly    17 TKAVLISILGVAIVLS---NLLIIATYANFKGPTEVINYYLLSLAIADLLCGLLVVPFSVYPALT 78
            ::.:|.::.|...||:   |||::.:..:|:......|:.:.|||.||||.||.|:|||:..::.
  Rat    46 SRLILYAVFGFGAVLAVCGNLLVMTSILHFRQLHSPANFLVASLACADLLVGLTVMPFSMVRSVE 110

  Fly    79 GEWMYGDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLRYETVQTKTRCQCWMVFTW--- 140
            |.|.:|:..|:|....|.:....|::...:||:|||:||..||.|.|..|.:.....:.|:|
  Rat   111 GCWYFGNTYCKFHSCFEGSFCYSSLFHLCFISLDRYIAVSDPLIYPTRFTASISGKCITFSWLLS 175

  Fly   141 -------------------ISAALLCCPPILGYSMPIENNMTHICMLDWGNMAAYSATLAILVLG 186
                               :.:||.|   :.|..:.:..:...|..|              |.|.
  Rat   176 IIYSFSLLYTGANEAGLEDLVSALTC---VGGCQVAVNQSWVFINFL--------------LFLV 223

  Fly   187 PSLISIVHNYGYIFVMMRK------------IRSGEPIHDKEYATALAENLSNPSHMMSFALVFA 239
            |:|: ::..|..||::.::            .|:.|...|:     :|:.....:..:..| |.|
  Rat   224 PALV-MMTVYSKIFLIAKQQAQNIEKMSKQTARASESYKDR-----VAKRERKAAKTLGIA-VAA 281

  Fly   240 FWVSWLPWILLRLYEVVTGDVIQSTLINFAVVWIGILNSFWKILIMTSMSPQFRIALRV 298
            |.:||||:.:..:.:...| .|..|.:...:|||...||....||.....|.||.|:::
  Rat   282 FLLSWLPYFIDSIIDAFLG-FITPTYMYEILVWIVYYNSAMNPLIYAFFYPWFRKAIKL 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DopEcR	NP_647897.2	7tm_classA_rhodopsin-like	18..289	CDD:410626	78/307 (25%)
		TM helix 1	18..43	CDD:410626	7/27 (26%)
		TM helix 2	50..76	CDD:410626	14/25 (56%)
		TM helix 3	88..118	CDD:410626	10/29 (34%)
		TM helix 4	131..150	CDD:410626	5/40 (13%)
		TM helix 5	173..198	CDD:410626	5/24 (21%)
		TM helix 6	224..254	CDD:410626	8/29 (28%)
		TM helix 7	264..289	CDD:410626	8/24 (33%)
Taar7c	NP_001009975.1	7tm_GPCRs	49..337	CDD:475119	81/312 (26%)
		TM helix 1	50..74	CDD:410628	7/23 (30%)
		TM helix 2	83..105	CDD:410628	13/21 (62%)
		TM helix 3	121..143	CDD:410628	4/21 (19%)
		TM helix 4	166..182	CDD:410628	2/15 (13%)
		TM helix 5	210..233	CDD:410628	6/37 (16%)
		TM helix 6	272..294	CDD:410628	8/22 (36%)
		TM helix 7	305..330	CDD:410628	8/24 (33%)