DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DopEcR and Olr640

DIOPT Version :9

Sequence 1:	NP_001014559.1	Gene:	DopEcR / 38539	FlyBaseID:	FBgn0035538	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001000644.1	Gene:	Olr640 / 404840	RGDID:	1332952	Length:	309	Species:	Rattus norvegicus

Alignment Length:	336	Identity:	69/336 - (20%)
Similarity:	127/336 - (37%)	Gaps:	94/336 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 QDNSKVEALTKAVLISILGVAIVLSNLLIIATY---ANFKGPTEVINYYLLSLAIADLLCG---- 65
            ||:.|.:|:....|  ||.:..:|.|.||:.|.   ....||   :.::|..|:.||....
  Rat    17 QDSEKQKAIFGVFL--ILYLMTLLGNFLIVVTIKMSQTLGGP---MYFFLFYLSFADACFSTTTA 76

  Fly    66 --LLVVPFSVYPALT-GEWMYGDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLRYETVQ 127
              |:|..|.....:| .|.|.......|.|.:|       ::..:.::.|||:|:.|||||.|:.
  Rat    77 PRLIVDSFFQKKIITYNECMTQIFAGHFFGCME-------IFVLILMAFDRYVAICKPLRYTTIM 134

  Fly   128 TKTRCQCWMVFTWISAAL-------------LCCPPILGY-------------------SMPIEN 160
            .:..|...::..|:.:.:             .|.|.::.:                   ::.:.:
  Rat   135 NQRICGILVILAWVGSCIHSSAQIFLALRLPFCGPNVIDHFSCDLQPLLKLACIDTYVINLLVVS 199

  Fly   161 NMTHICMLDWGNMAAYSATLAILVLGPSLISIVHNYGYIFVMMRKIRSGEPIHDKEYATALAENL 225
            |...|||            ::.:||..|.|.|:::.        |..|.|. ..|..:|.
  Rat   200 NSGAICM------------VSFIVLFVSYIVILYSL--------KNHSAEG-RRKALSTC----- 238

  Fly   226 SNPSHMMSFALVFAFWVSWLPWILLRLYEVVTGDVIQSTLINFAVVWIGILNSFWKILIMTSMSP 290
              .||.:...:.|.      |.|.:....::|..:.:...: |..:...:||.    ||.|..:.
  Rat   239 --TSHFIVVVIFFG------PCIFIYTRPLITLPIDKMVSV-FYTIATPLLNP----LIYTLRNA 290

  Fly   291 QFRIAL-RVFC 300
            :.:.|: :::|
  Rat   291 EVKNAMKKIWC 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DopEcR	NP_001014559.1	7tm_classA_rhodopsin-like	18..289	CDD:410626	63/312 (20%)
		TM helix 1	18..42	CDD:410626	8/26 (31%)
		TM helix 2	51..73	CDD:410626	7/27 (26%)
		TM helix 3	89..111	CDD:410626	3/21 (14%)
		TM helix 4	134..150	CDD:410626	2/28 (7%)
		TM helix 5	174..197	CDD:410626	5/22 (23%)
		TM helix 6	230..252	CDD:410626	4/21 (19%)
		TM helix 7	264..289	CDD:410626	6/24 (25%)
Olr640	NP_001000644.1	7tm_4	29..303	CDD:304433	65/324 (20%)
Olr640	NP_001000644.1	7tm_1	39..285	CDD:278431	57/294 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1099557at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010