DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DopEcR and Octbeta3R

DIOPT Version :9

Sequence 1:	NP_001014559.1	Gene:	DopEcR / 38539	FlyBaseID:	FBgn0035538	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_001034048.2	Gene:	Octbeta3R / 3885573	FlyBaseID:	FBgn0250910	Length:	1256	Species:	Drosophila melanogaster

Alignment Length:	234	Identity:	67/234 - (28%)
Similarity:	99/234 - (42%)	Gaps:	38/234 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LTKAVLISILGVAIVLSNLLIIATYANFKGPTEVINYYLLSLAIADLLCGLLVVPFSVYPALT-G 79
            |.|..:.|.:.:|.||.|.|:|.:....:....:.||:::|||:||:|..|..:.|:....|: |
  Fly   140 LLKGFIFSSIILAAVLGNALVIISVQRNRKLRVITNYFVVSLAMADMLVALCAMTFNASVELSGG 204

  Fly    80 EWMYGDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLRYETVQT-KTRCQCWMVFTWISA 143
            :||:|..:|.....|:|.....|:.....||||||.|:.:||.|....| ||.| ..:...||..
  Fly   205 KWMFGPFMCNVYNSLDVYFSTASILHLCCISVDRYYAIVRPLEYPLNMTHKTVC-FMLANVWILP 268

  Fly   144 ALLCCPPILGYSMPIENNMTHICMLDWGNMAAYSATLAILVLGPSLISIVHNYGY---------- 198
            ||:...||               .|.|.....:   |..:.|.|...|.|.|..|
  Fly   269 ALISFTPI---------------FLGWYTTEEH---LREISLHPDQCSFVVNKAYALISSSVSFW 315

  Fly   199 -----IFVMMRKIRSGEPIHDKEYATALAEN-LSNPSHM 231
                 :.||..:|.. |.|..::..:..:.| |.|..||
  Fly   316 IPGIVMLVMYWRIFK-EAIRQRKALSRTSSNILLNSVHM 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DopEcR	NP_001014559.1	7tm_classA_rhodopsin-like	18..289	CDD:410626	66/232 (28%)
		TM helix 1	18..42	CDD:410626	8/23 (35%)
		TM helix 2	51..73	CDD:410626	10/21 (48%)
		TM helix 3	89..111	CDD:410626	4/21 (19%)
		TM helix 4	134..150	CDD:410626	4/15 (27%)
		TM helix 5	174..197	CDD:410626	6/22 (27%)
		TM helix 6	230..252	CDD:410626	2/2 (100%)
		TM helix 7	264..289	CDD:410626
Octbeta3R	NP_001034048.2	7tm_4	146..>346	CDD:304433	60/219 (27%)
Octbeta3R	NP_001034048.2	7tm_1	156..>344	CDD:278431	56/207 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460663
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24248
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030