DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DopEcR and Adra2c

DIOPT Version :9

Sequence 1:	NP_001014559.1	Gene:	DopEcR / 38539	FlyBaseID:	FBgn0035538	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_612515.2	Gene:	Adra2c / 24175	RGDID:	2058	Length:	458	Species:	Rattus norvegicus

Alignment Length:	136	Identity:	40/136 - (29%)
Similarity:	70/136 - (51%)	Gaps:	0/136 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 AVLISILGVAIVLSNLLIIATYANFKGPTEVINYYLLSLAIADLLCGLLVVPFSVYPALTGEWMY 83
            |.::..|.|..|:.|:|::......:......|.:|:|||.||:|...||:|||:...|...|.:
  Rat    55 AAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYF 119

  Fly    84 GDIVCRFTGYLEVTLWAVSVYTFMWISVDRYLAVRKPLRYETVQTKTRCQCWMVFTWISAALLCC 148
            |.:.|.....|:|.....|:.....||:|||.:|.:.:.|...:|..|.:..:|..|:.:|::..
  Rat   120 GQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISF 184

  Fly   149 PPILGY 154
            ||::.:
  Rat   185 PPLVSF 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DopEcR	NP_001014559.1	7tm_classA_rhodopsin-like	18..289	CDD:410626	40/136 (29%)
		TM helix 1	18..42	CDD:410626	6/22 (27%)
		TM helix 2	51..73	CDD:410626	12/21 (57%)
		TM helix 3	89..111	CDD:410626	4/21 (19%)
		TM helix 4	134..150	CDD:410626	3/15 (20%)
		TM helix 5	174..197	CDD:410626
		TM helix 6	230..252	CDD:410626
		TM helix 7	264..289	CDD:410626
Adra2c	NP_612515.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	245..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000