DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11342 and LOC568375

DIOPT Version :9

Sequence 1:	NP_647896.1	Gene:	CG11342 / 38538	FlyBaseID:	FBgn0035537	Length:	238	Species:	Drosophila melanogaster
Sequence 2:	XP_017208938.1	Gene:	LOC568375 / 568375	-ID:	-	Length:	254	Species:	Danio rerio

Alignment Length:	243	Identity:	79/243 - (32%)
Similarity:	131/243 - (53%)	Gaps:	12/243 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NNDPGAVQYGNFFNYYQFSSAAERVKLLPDADIWLPALEDGETQKDKPYFILDVGCNCGVLTQLM 69
            :.:|||..||||.|||.|:....|:.|:|:|.:.......|:.::   ..:||||||.|.|:..:
Zfish    13 SENPGAAPYGNFINYYTFNPPENRLSLIPEALLQNIGFTSGDGER---VLMLDVGCNSGDLSVAL 74

  Fly    70 HKYL-------EERLHRSVKVLGVDIDPRLIQRASEENESPKDVSYACVDVLDD-EAFESVKTYM 126
            :|:|       .:...:.:.:||.|:|..||.||...|..|:::.:..:|:.|| |:...::.::
Zfish    75 YKHLLNKEACTSDSPRQELYMLGFDLDQDLILRAQTSNPFPQNIQFIPLDITDDTESRAVLQAFL 139

  Fly   127 EVNNLEKFDAICCYSITMWIHLNHHDQGLRFFLQKLSNLAELLVVEPQPWKCYQKAERRLKKAGE 191
            ......:|....|:::|||:||||.|......|.:|::.:|.|::|.||||||:.|.|||:|.|.
Zfish   140 GKFGCSRFHLSTCFAVTMWVHLNHGDAAFLSLLSRLASHSEYLLLEAQPWKCYRSAARRLRKLGR 204

  Fly   192 I-FPLFLELKWRSDVDLQIQKYLEESLDRRKIFKSAPTKWQRKICFYR 238
            . |..|..||.|.|:....:::||:......:.....|.|.|.:..:|
Zfish   205 SDFDHFKALKIRGDMAAHAREHLEKQCSMELVQCFGNTSWDRSLLLFR 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11342	NP_647896.1	Methyltransf_12	56..165	CDD:285454	36/116 (31%)
CG11342	NP_647896.1	AdoMet_MTases	134..238	CDD:302624	38/104 (37%)
LOC568375	XP_017208938.1	AdoMet_MTases	152..252	CDD:302624	37/99 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589287
Domainoid	1	1.000	82	1.000	Domainoid score	I8382
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12594
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4372
OMA	1	1.010	-	-		QHG45376
OrthoDB	1	1.010	-	-		D1185441at2759
OrthoFinder	1	1.000	-	-		FOG0007133
OrthoInspector	1	1.000	-	-		oto40310
orthoMCL	1	0.900	-	-		OOG6_110142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4485
SonicParanoid	1	1.000	-	-		X5229
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.840