DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cip4 and LSB3

DIOPT Version :9

Sequence 1:	NP_001097501.1	Gene:	Cip4 / 38534	FlyBaseID:	FBgn0035533	Length:	665	Species:	Drosophila melanogaster
Sequence 2:	NP_219497.4	Gene:	LSB3 / 850580	SGDID:	S000002968	Length:	459	Species:	Saccharomyces cerevisiae

Alignment Length:	306	Identity:	77/306 - (25%)
Similarity:	111/306 - (36%)	Gaps:	95/306 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   388 FNIFGSNKNSLTADGQKED-------FSDLP------------PNQR--RKKLQAKIAELTQNIA 431
            ||...||....:.|..::|       ::|:|            ||.|  |::.|:.......:..
Yeast   216 FNYRPSNGGRGSFDDDEDDYYDDDDYYNDIPSSFSSTDASSTRPNTRSTRRRAQSGSRYTFDDDD 280

  Fly   432 QETKARDGLMKMKIVYEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSS 496
            .:.....|       |..||.|. |....|    |..||:.                  |:..||
Yeast   281 DDDDYGTG-------YSRNSRLA-PTNSGG----SGGKLDD------------------PSGASS 315

  Fly   497 PQASRNQ---LQNGHRTSRHSNGSADDHHDDGDDQPDDAGSLSRSDSED-----NVAQIQNGHNN 553
            ..||..:   .|:..|:||  |..|||.:||.||  |......|.:..|     .|..:.|..:.
Yeast   316 YYASHRRSGTAQSRARSSR--NRWADDEYDDYDD--DYESGYRRGNGRDRTKDREVDDLSNRFSK 376

  Fly   554 NNNGSASPESGLGTSHTSLPGSGQGSANENAIGEDTYYETEVETLNPVGKCRALYPFEASSEGSI 618
            :...|||      |..||   .|:.:|           .|...|.:|  |..|||.|.....|.:
Yeast   377 SRISSAS------TPQTS---QGRFTA-----------PTSPSTSSP--KAVALYSFAGEESGDL 419

  Fly   619 PMSEGEELQVIE--IDQGDGWT-RVRRENNSNGWDEGFVPTSYIEI 661
            |..:|:.:.:::  ..|.|.|| ||      || .||..|.:|:|:
Yeast   420 PFRKGDVITILKKSDSQNDWWTGRV------NG-REGIFPANYVEL 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337
		HR1_CIP4-like	412..488	CDD:212009	15/77 (19%)
		SH3_CIP4-like	603..661	CDD:212844	20/60 (33%)
LSB3	NP_219497.4	SYLF	1..219	CDD:225482	2/2 (100%)
LSB3	NP_219497.4	SH3_Ysc84p_like	404..458	CDD:212776	20/60 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030