Protein Alignment Cip4 and sh3d19

DIOPT Version :9

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_009289295.1
• Gene: sh3d19 / 553811
• ZFINID: ZDB-GENE-050522-481
• Length: 963
• Species: Danio rerio
• Alignment Length: 788
• Identity: 146/788 - (18%)
• Similarity: 242/788 - (30%)
• Gaps: 285/788 - (36%)

  Fly    53 AESENSAQNS-NNMSWGTELWDQN--ENLAI-HTNRGI--------------------------- 86
            :|.::...|. ||....|.|.::|  ||:.. |::|.|
Zfish   273 SEPQSELSNPVNNQGEQTNLTNENQIENMTFHHSDRNIRSRIQAFESQAATENDAASVPFPRPRK 337

  Fly    87 -------------------------DALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKKKEEED 126
                                     :...:|.:.|.:.:.:|...|.: .:|.|......:||.|
Zfish   338 IGAKPPILAPKPSIAPRPSVIKPKEEPFSQFDSHLYEELDMEPTPAPR-PQLFKKPSLDSREESD 401

  Fly   127 NE---FTSVQAFRNLLKEVGDLAGQREVV---------------------SESLQLQIIAGVTLL 167
            ::   .|::.:..:|:|.....:...|||                     |.:|...:.:.|.:|
Zfish   402 SQPFFKTALTSRPSLVKHKNVYSQDEEVVVKGPIPPLKPSKDLLNANNHNSTALLPDLTSAVNVL 466

  Fly   168 SK-----TLREERKKCLSDGATLQQNLTTQLSSLDR--------AKRNYEKAYRDSEKAVD---- 215
            |.     ::.....|.:..|........||  ::.|        :|.:...|:.|||:||:
Zfish   467 SNDYVDTSINHSPTKPVRQGGFSYMGGNTQ--AVTRRPTVIRVPSKTDKISAFSDSEEAVEFPPP 529

  Fly   216 ---------------SYKR------ADMDL-------------------NLSRAEVERYKNVMTS 240
                           ::::      :||.:                   ...|....:..|   |
Zfish   530 LPVQKAVGSTPTPAKAFRQDPFNVSSDMSIPPRPSGGKVLPPRPPPAKTGPGRPPPPQTNN---S 591

  Fly   241 KIQQSDDAKNEYANQLQKTNNLQQQH-----YSMLLPSVLNRLQELDEKRT----RGFREFIVGA 296
            :.:.||...::.|...|:.:..|||:     ....||...|....|..|.|    .|..||
Zfish   592 QRRPSDSGFSQIAPSKQQPSQWQQQNRRASKKGPALPPRPNPGHRLYNKYTLEVPHGIAEF---- 652

  Fly   297 ADVESSVAPIIARCMEGIVKAGESINEKEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSH 361
             |...|             ..||...:|.:...::|...|.       .||..:.....:||.||
Zfish   653 -DYNGS-------------NTGELSFQKNEVLVLLEELDSR-------TFECQAGNTKGTVQKSH 696

  Fly   362 YSNSTSNHLTIRGTMSANKLKKRVGIFNIFGSNKNSLTADGQKEDFSDLPPNQRRKKLQAKIAEL 426
            ....|.  ||   .:|:|.|.::...|...|.|..||..:. ..||:...|.:    |..|..::
Zfish   697 MKIITP--LT---DLSSNSLPQKTSSFRGMGGNAGSLQVEA-LYDFTPAGPGE----LALKAGDV 751

  Fly   427 TQNIAQETKARDGLMKMKIVYEANSSLGNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKAS--- 488
            ..|:.|                                          :|...|.|....|:
Zfish   752 VSNVEQ------------------------------------------LDDDWYMGTCRNATGFF 774

  Fly   489 --QVPTATSSPQ----ASRNQLQN--GHRTSRHSNGSA--DDHHDDGDDQPDDAGSLSRSDSEDN 543
              ......|.|.    |.||:.:|  ...|.|.....|  |...:.||:         .|..||:
Zfish   775 PINYVKVLSKPNIYAPAFRNEWKNKPSPETVRGPRCVARFDFEGEQGDE---------LSFFEDD 830

  Fly   544 VAQIQ--------NGHNNNNNG-------------SASPESGLGTSHTSLPGSGQGSANENAIGE 587
            |.|::        .|..|.:.|             .:.|......:..:|||....|.      :
Zfish   831 VIQLKEYLGEEWARGEVNGHVGIFPLNFVEVIEDLPSVPVQKSAPNKIALPGMASSST------Q 889

  Fly   588 DTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEGEELQVIEIDQGDGWTRVRRENNSNGWDEG 652
            .:|..:|.|: |......|||.|.|.:|..:|..:|:.:.|......:.|:     ...|| .||
Zfish   890 SSYRASEAES-NGAEWAVALYDFTAETEEDLPFQQGDRILVTAHVDDEWWS-----GRING-REG 947

  Fly   653 FVPTSYIE 660
            |.|.:::|
Zfish   948 FFPKAFVE 955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	63/394 (16%)
		HR1_CIP4-like	412..488	CDD:212009	8/75 (11%)
		SH3_CIP4-like	603..661	CDD:212844	17/58 (29%)
sh3d19	XP_009289295.1	SH3	647..696	CDD:302595	14/73 (19%)
		SH3	732..782	CDD:302595	11/96 (11%)
		SH3_Eve1_3	809..859	CDD:212750	12/58 (21%)
		SH3_Eve1_4	904..953	CDD:212751	16/54 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2056
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030