| Sequence 1: | NP_001097501.1 | Gene: | Cip4 / 38534 | FlyBaseID: | FBgn0035533 | Length: | 665 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001157945.1 | Gene: | FNBP1L / 54874 | HGNCID: | 20851 | Length: | 605 | Species: | Homo sapiens |
| Alignment Length: | 675 | Identity: | 229/675 - (33%) |
|---|---|---|---|
| Similarity: | 348/675 - (51%) | Gaps: | 153/675 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 65 MSWGTELWDQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKK-KEEEDNE 128
Fly 129 FTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQNLTTQL 193
Fly 194 SSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEYANQLQK 258
Fly 259 TNNLQQQHYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVKAGESINE 323
Fly 324 KEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSHYSNSTSNHLTIRGTMSANK-------- 380
Fly 381 ---LKKRVGIFNIFGSNK-------------NSLTADGQK------------------------- 404
Fly 405 ----------------EDFSDLPPNQRRKKLQAKIAELTQNIAQETKARDGLMKMKIVYEANSSL 453
Fly 454 GNPMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSSPQASRNQLQNGHRTSRHSNGSA 518
Fly 519 DDHH--DDGDDQP-----DDAGSLSRSDSEDNVAQIQNGHNNNNNGSASPESGLGTSHTSLPGSG 576
Fly 577 QGSANENAIGEDTYYETEVETLNP---VGKCRALYPFEASSEGSIPMSEGEELQVIEIDQGDGWT 638
Fly 639 RVRRENNSNGWDEGFVPTSYIEITL 663 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Cip4 | NP_001097501.1 | F-BAR_CIP4-like | 69..319 | CDD:153337 | 105/250 (42%) |
| HR1_CIP4-like | 412..488 | CDD:212009 | 28/75 (37%) | ||
| SH3_CIP4-like | 603..661 | CDD:212844 | 32/57 (56%) | ||
| FNBP1L | NP_001157945.1 | F-BAR_FNBP1L | 5..256 | CDD:153359 | 105/250 (42%) |
| Interaction with CDC42 | 245..535 | 88/362 (24%) | |||
| HR1_CIP4_FNBP1L | 399..479 | CDD:212018 | 31/82 (38%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 476..539 | 20/118 (17%) | |||
| Interaction with DNM1. /evidence=ECO:0000269|PubMed:16326391 | 522..605 | 41/117 (35%) | |||
| Interaction with DAAM1, DIAPH1 and DIAPH2. /evidence=ECO:0000269|PubMed:16630611 | 541..605 | 35/62 (56%) | |||
| Interaction with DNM2 and WASL. /evidence=ECO:0000269|PubMed:16418535 | 541..597 | 33/59 (56%) | |||
| SH3_FNBP1L | 541..597 | CDD:213005 | 33/59 (56%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165157760 | |
| Domainoid | 1 | 1.000 | 213 | 1.000 | Domainoid score | I2748 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG3565 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 359 | 1.000 | Inparanoid score | I2217 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG51860 | |
| OrthoDB | 1 | 1.010 | - | - | D348563at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001169 | |
| OrthoInspector | 1 | 1.000 | - | - | otm40537 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_103782 | |
| Panther | 1 | 1.100 | - | - | O | PTHR15735 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2056 |
| SonicParanoid | 1 | 1.000 | - | - | X890 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.800 | |||||