Protein Alignment Cip4 and trip10a

DIOPT Version :10

• Sequence 1: NP_001097501.1
• Gene: Cip4 / 38534
• FlyBaseID: FBgn0035533
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_017209563.1
• Gene: trip10a / 492762
• ZFINID: ZDB-GENE-041114-105
• Length: 592
• Species: Danio rerio
• Alignment Length: 668
• Identity: 219/668 - (32%)
• Similarity: 337/668 - (50%)
• Gaps: 147/668 - (22%)

  Fly    65 MSWGTELWDQNENLAIHTNRGIDALDKFANFLRDRVAIETEYAGKLRRLVKNYQPKK--KEEEDN 127
            |.||||||||.:.|..||..|:|.:||:..|:::|..||..||.:||.|.|.|.||:  |||::.
Zfish     1 MDWGTELWDQYDILDKHTQSGLDLVDKYMKFVKERTDIEQNYAKQLRNLTKKYSPKRGSKEEQEC 65

  Fly   128 EFTSVQAFRNLLKEVGDLAGQREVVSESLQLQIIAGVTLLSKTLREERKKCLSDGATLQQNLTTQ 192
            .|::.|||.::|.|:.|.|||||:::|::.:.|...:....:.|::|||..||:....||:|...
Zfish    66 RFSNHQAFLDILNEMNDYAGQRELIAENMMINICVELNKYLQELKQERKMHLSEAKKSQQSLEAM 130

  Fly   193 LSSLDRAKRNYEKAYRDSEKAVDSYKRADMDLNLSRAEVERYKNVMTSKIQQSDDAKNEYANQLQ 257
            ...||.:|:.:|:.:|::|||.....:.|.|||.::|:||:.|.....:...::|.||:||.|||
Zfish   131 YKQLDNSKKRFEREWREAEKAAQYADKTDQDLNATKADVEKAKQQAHLRTHIAEDCKNDYAVQLQ 195

  Fly   258 KTNNLQQQHYSMLLPSVLNRLQELDEKRTRGFREFIVGAADVESSVAPIIARCMEGIVKAGESIN 322
            |.|..|.|.|...:|.:.|:||::||:|.:...:..:..|:.|..|.|||.:|:||:.:||.::|
Zfish   196 KYNKEQSQFYFTDMPQIFNKLQDMDERRIKKMAQGYILFAETERHVMPIIGKCLEGMTRAGTNVN 260

  Fly   323 EKEDTFKVIERYQSGFTPPRDIPFEDLSKCDPDSVQDSHYSNSTSNHLTIRGTMSANKLKKRVGI 387
            .:.|:..:||:::|||..|.|:.|||.|       |..:.::|.|:..|.:|.:
Zfish   261 ARNDSMVLIEQHKSGFERPGDLDFEDYS-------QGINRASSDSSLGTPKGPL----------- 307

  Fly   388 FNIFGSNKN---------------SLT----------ADG------------------------- 402
             .:.|.|||               ||:          |:|
Zfish   308 -ELLGKNKNKTFRLFNKKSKLPSSSLSPYSTPPIPSPANGPPSPKFGRDPLSYCLKEINKTVKPR 371

  Fly   403 ------------QKEDFSDLPPNQRRKKLQAKIAELTQNIAQETKARDGLMKMKIVYEANSSLGN 455
                        ..|.|:.|||.||||:||.||.::::.:.:|....:.|.|||.|||.|..:|:
Zfish   372 ISSFRTLKRTPVDTEGFTHLPPEQRRKRLQQKIDDMSKELQKEMDQSEALGKMKDVYEKNPQMGD 436

  Fly   456 PMTVEGQLNESEHKLEKLKVDLKKYQGFLEKASQVPTATSSPQASRNQLQNGHRTSRHSNGSADD 520
            |.::..|:.::...:::|:.:|.||:.:|.:|.
Zfish   437 PASLAPQIGQTAQNMDRLRGELNKYESWLAEAG-------------------------------- 469

  Fly   521 HHDDGDDQPDDAGSLSRSDSEDNVAQIQ-NGHNNNNNGSASPESGLGTSHTSLPGSGQGSAN-EN 583
                           .|.||      |: :.|:.||||:.:|.|..|:.....||:.....: ..
Zfish   470 ---------------GRGDS------IRYSTHSINNNGAHNPNSNDGSCTLFSPGALSDETDPSQ 513

  Fly   584 AI---GEDTYYETEVETLNPVGKCRALYPFEASSEGSIPMSEGEELQVIEIDQGDGWTRVRRENN 645
            ||   .:|.:.|.|:.|  |:|:|.|||.|..||||:|.|.|||.|.|:|.|:|||||||||.|.
Zfish   514 AIYTEFDDEFEEEELAT--PIGQCTALYNFPGSSEGTISMQEGEVLAVVEEDKGDGWTRVRRNNG 576

  Fly   646 SNGWDEGFVPTSYIEITL 663
                |||::||||..|||
Zfish   577 ----DEGYIPTSYATITL 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cip4	NP_001097501.1	F-BAR_CIP4-like	69..319	CDD:153337	98/251 (39%)
		HR1_CIP4-like	412..488	CDD:212009	26/75 (35%)
		SH3_CIP4-like	603..661	CDD:212844	35/57 (61%)
trip10a	XP_017209563.1	F-BAR_CIP4-like	5..257	CDD:153337	98/251 (39%)
		HR1_CIP4_FNBP1L	392..472	CDD:212018	28/126 (22%)
		SH3_CIP4-like	534..588	CDD:212844	35/57 (61%)